Mutants (Isolated)

tm1802

Allele Name

tm1802

Sequence Name

R53.3

CGC Name

egl-43

Worm Base

Allele Name

tm1802

CGC Name

egl-43

Sequence

R53.3

Phenotype

lethal or sterile. Dr. P.W. Sternberg: Development 134, 669 (2007). Dr.A. Hajnal: Dev. Biol. 308, 187 (2007).

Mutation site

18540/18541-ACT-19077/19078 (537 bp deletion + 3 bp insertion)

Chromosome

Putative gene structure

join(12631..12750, 14458..14559, 14615..14745, 16034..16195, 17196..17310, 17746..17931, 18385..18482, 18633..19137, 19275..19346, 19459..19599)

Map position

1.82

Balancer

Not Yet Balanced

Map position of balancer

Sequence of primers

ExtFwd:CGTGCAATGCTCCTGGGCTA,IntRev:TGCGGGGGGTTACTGTAGCA,ExtRev:TTGTGGGGTGTCAGCGAGGT,IntFwd:ACCCCATAATCTCACAACAG

Distributed lab

Depositor

Dr. S. Mitani

References

Please submit your publication

Medwig-Kinney TN, Smith JJ, Palmisano NJ, Tank S, Zhang W, Matus DQ.
A developmental gene regulatory network for C. elegans anchor cell invasion.
Development 2020 147(1)
[ PubMed ID = 31806663 ] [ RRC reference ]

Deng T, Stempor P, Appert A, Daube M, Ahringer J, Hajnal A, Lattmann E.
The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion.
PLoS Genet 2020 16(3) e1008470
[ PubMed ID = 32203506 ] [ RRC reference ]

Rimann I, Hajnal A.
Regulation of anchor cell invasion and uterine cell fates by the egl-43 Evi-1 proto-oncogene in Caenorhabditis elegans.
Dev Biol 2007 308(1) 187-95
[ PubMed ID = 17573066 ] [ RRC reference ]

Hwang BJ, Meruelo AD, Sternberg PW.
C. elegans EVI1 proto-oncogene, EGL-43, is necessary for Notch-mediated cell fate specification and regulates cell invasion.
Development 2007 134(4) 669-79
[ PubMed ID = 17215301 ] [ RRC reference ]