Mutants (Isolated)


Allele Nametm1688
Sequence NameT24B8.6
CGC Namehlh-3
Worm BaseAllele Name tm1688
CGC Name hlh-3
Sequence T24B8.6
Phenotypehomozygous viable
Mutation site35589/35590-36831/36832 (1242 bp deletion)
Putative gene structurejoin(35567..35662, 36199..36396, 36888..37205)
Map position1
Map position of balancer
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Perez LM, Alfonso A.
The Conserved ASCL1/MASH-1 Ortholog HLH-3 Specifies Sex-Specific Ventral Cord Motor Neuron Fate in Caenorhabditis elegans.
G3 (Bethesda) 2020 10(11) 4201-4213 
[ PubMed ID = 32973001 ] [ RRC reference ]

Masoudi N, Tavazoie S, Glenwinkel L, Ryu L, Kim K, Hobert O.
Unconventional function of an Achaete-Scute homolog as a terminal selector of nociceptive neuron identity.
PLoS Biol 2018 16(4) e2004979 
[ PubMed ID = 29672507 ] [ RRC reference ]

Lloret-Fernández C, Maicas M, Mora-Martínez C, Artacho A, Jimeno-Martín Á, Chirivella L, Weinberg P, Flames N.
A transcription factor collective defines the HSN serotonergic neuron regulatory landscape.
Elife 2018 7  
[ PubMed ID = 29553368 ] [ RRC reference ]

Luo S, Horvitz HR.
The CDK8 Complex and Proneural Proteins Together Drive Neurogenesis from a Mesodermal Lineage.
Curr Biol 2017 27(5) 661-672 
[ PubMed ID = 28238659 ] [ RRC reference ]

Li Y, Zhao D, Horie T, Chen G, Bao H, Chen S, Liu W, Horie R, Liang T, Dong B, Feng Q, Tao Q, Liu X.
Conserved gene regulatory module specifies lateral neural borders across bilaterians.
Proc Natl Acad Sci U S A 2017 114(31) E6352-E6360 
[ PubMed ID = 28716930 ] [ RRC reference ]

Sallee MD, Littleford HE, Greenwald I.
A bHLH Code for Sexually Dimorphic Form and Function of the C. elegans Somatic Gonad.
Curr Biol 2017 27(12) 1853-1860.e5 
[ PubMed ID = 28602651 ] [ RRC reference ]

Murgan S, Kari W, Rothbächer U, Iché-Torres M, Mélénec P, Hobert O, Bertrand V.
Atypical Transcriptional Activation by TCF via a Zic Transcription Factor in C. elegans Neuronal Precursors.
Dev Cell 2015 33(6) 737-45 
[ PubMed ID = 26073017 ] [ RRC reference ]

Doonan R, Hatzold J, Raut S, Conradt B, Alfonso A.
HLH-3 is a C. elegans Achaete/Scute protein required for differentiation of the hermaphrodite-specific motor neurons.
Mech Dev 2008 125(9-10) 883-93 
[ PubMed ID = 18586090 ] [ RRC reference ]