Mutants (Isolated)

tm1615

Allele Nametm1615
Sequence NameF08B4.1
CGC Namedic-1
Worm BaseAllele Name tm1615
CGC Name dic-1
Sequence F08B4.1
Phenotypelethal or sterile. Dr. H-S. Koo: larval arrest at the L3 stage.Development 133, 3597 (2006)
Mutation site32904/32905-33492/33493 (588 bp deletion)
ChromosomeIV
Putative gene structurejoin(31989..32099, 32146..32241, 32357..32674, 32734..32950, 33042..33204, 33285..33453, 33544..33765, 33844..34032, 34083..34205, 34248..34348, 34724..34840, 35115..35562, 35691..35787, 35845..35993)
Map position3.94
BalancernT1 [qIs51]
Map position of balancer
Sequence of primersExtFwd:GCGTACTTTGTAGCGAACCT,IntFwd:GCGAACCTGACGCGCAATAA,ExtRev:GGCGATAGCCATTTGATCTA,IntRev:GGTCCATTTGATGAACCTTC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Gómez-Orte E, Sáenz-Narciso B, Zheleva A, Ezcurra B, de Toro M, López R, Gastaca I, Nilsen H, Sacristán MP, Schnabel R, Cabello J.
Disruption of the Caenorhabditis elegans Integrator complex triggers a non-conventional transcriptional mechanism beyond snRNA genes.
PLoS Genet 2019 15(2) e1007981 
[ PubMed ID = 30807579 ] [ RRC reference ]

Beltran T, Pahita E, Ghosh S, Lenhard B, Sarkies P.
Integrator is recruited to promoter-proximally paused RNA Pol II to generate Caenorhabditis elegans piRNA precursors.
EMBO J 2021 40(5) e105564 
[ PubMed ID = 33340372 ] [ RRC reference ]

Bustos AVG, Jiménez MG, Mora RMS.
The Annona muricata leaf ethanol extract affects mobility and reproduction in mutant strain NB327 Caenorhabditis elegans.
Biochem Biophys Rep 2017 10 282-286 
[ PubMed ID = 28955756 ] [ RRC reference ]

Han SM, Lee TH, Mun JY, Kim MJ, Kritikou EA, Lee SJ, Han SS, Hengartner MO, Koo HS.
Deleted in cancer 1 (DICE1) is an essential protein controlling the topology of the inner mitochondrial membrane in C. elegans.
Development 2006 133(18) 3597-606 
[ PubMed ID = 16914495 ] [ RRC reference ]