Mutants (Isolated)

tm1421

Allele Name

tm1421

Allele Type

Normal

Sequence Name

F43E2.5

Gene Name

msra-1

Worm Base

Allele Name

tm1421

Gene Name

msra-1

Sequence

F43E2.5

Phenotype

homozygous viable. Dr. M. Driscoll: No significant effects on age-related muscle decline.

Mutation site

12937/12938-13850/13851 (913 bp deletion)

Chromosome

Putative gene structure

complement(join(13045..13419, 13553..13801))

Map position

0.5

Balancer

Map position of balancer

Sequence of primers

ExtRev:TCTGAGCAGGTGTCACAGTG,IntRev:CAGACTGAGCCAGTCTTACT,ExtFwd:GCCACTGTCTTCGTCCAGGA,IntFwd:CCTTGCCGCCCGTCATTTAG

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Pinto C, Ibáñez MR, Loyola G, León L, Salvatore Y, González C, Barraza V, Castañeda F, Aldunate R, Contreras-Porcia L, Fuenzalida K, Bronfman FC.
Characterization of an Agarophyton chilense Oleoresin Containing PPARγ Natural Ligands with Insulin-Sensitizing Effects in a C57Bl/6J Mouse Model of Diet-Induced Obesity and Antioxidant Activity in Caenorhabditis elegans.
Nutrients 2021 13(6)
[ PubMed ID = 34071972 ] [ RRC reference ]

Minniti AN, Arriagada H, Zúñiga S, Bravo-Zehnder M, Alfaro IE, Aldunate R.
Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis.
Aging Cell 2019 18(1) e12855
[ PubMed ID = 30456853 ] [ RRC reference ]

Minniti AN, Arrazola MS, Bravo-Zehnder M, Ramos F, Inestrosa NC, Aldunate R.
The protein oxidation repair enzyme methionine sulfoxide reductase a modulates Aβ aggregation and toxicity in vivo.
Antioxid Redox Signal 2015 22(1) 48-62
[ PubMed ID = 24988428 ] [ RRC reference ]

Minniti AN, Cataldo R, Trigo C, Vasquez L, Mujica P, Leighton F, Inestrosa NC, Aldunate R.
Methionine sulfoxide reductase A expression is regulated by the DAF-16/FOXO pathway in Caenorhabditis elegans.
Aging Cell 2009 8(6) 690-705
[ PubMed ID = 19747232 ] [ RRC reference ]