Mutants (Isolated)

tm1415

Allele Nametm1415
Allele TypeNormal
Sequence NameAH9.2
Gene Namecrn-4
Worm BaseAllele Name tm1415
Gene Name crn-4
Sequence AH9.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 15094/15095-15608/15609 (514 bp deletion)
ChromosomeX
Putative gene structurecomplement(join(13959..14216, 15091..15249, 15307..15569, 15628..15706, 15755..15856, 15908..15943))
Map position-15.94
Balancer
Map position of balancer
Sequence of primersIntRev:CGACGTCGTTGCGCATCCAT,IntFwd:GTTGTAGACCAGCGGTTGTC,ExtRev:GCTCACTTGCTGCCTGTGTC,ExtFwd:CAGCGTCCATGAAGCTGCTT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Aruscavage PJ, Hellwig S, Bass BL.
Small DNA pieces in C. elegans are intermediates of DNA fragmentation during apoptosis.
PLoS One 2010 5(6) e11217 
[ PubMed ID = 20585459 ] [ RRC reference ]

Hsiao YY, Nakagawa A, Shi Z, Mitani S, Xue D, Yuan HS.
Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation.
Mol Cell Biol 2009 29(2) 448-57 
[ PubMed ID = 18981218 ] [ RRC reference ]