HOME MUTANTS CRE TRANSGENIC BALANCER PROMOTER SEARCH FAQ & CONTACT
ミニアンケート集計結果はこちら     MUTANTS
キーワード検索
分離済み変異体
スクリーニング中変異体
  

分離済み変異体
変異体一覧
項目検索
分譲申し込み方法
MTA
技術的なコメント
論文情報登録

スクリーニング中変異体
進行状況
スクリーニング申し込み方法
スクリーニング申し込み

フィードバック
フィードバックの
お願い
 
 
 

Last Update
null

 
staff only
AVAILABLE MUTANTS (ISOLATED)
 変異体 To English >>
 
Record No. 892
対立遺伝子 tm892
Sequence Name F20D12.1
CGC Name csr-1
Worm Base 対立遺伝子 tm892
CGC Name csr-1
Sequence F20D12.1
表現型 lethal or sterile. Dr. C. Mello, Cell 127, 747-457 (2006). Dr. E. Miska; Mol Cell 31, 79-90 (2008).
変異部位 26731/26372-27131/27132 (400 bp deletion)
染色体 IV
遺伝子構造 join(25568..26042, 26587..26746, 26788..26941, 26985..27196, 27241..27392, 27440..27825, 27871..28592, 28637..28736, 28781..29137, 29188..29376, 29420..29508, 29555..29651)
マップポジション 3.52
バランサ unc-24 (e138) IV
バランサマップポジション 3.52
プライマー配列 IntFwd:GCCCTGAACATCTTCGGGCT,ExtFwd:GGCCTTTCTCTGCGTTTAGT,ExtRev:CGCAGCGTTTCGGTCAGGAT,IntRev:TCAGGATGAGCAACGTCCAT
変異体送付先
寄託者 Dr. S. Mitani
文献  論文登録
Tu S, Wu MZ, Wang J, Cutter AD, Weng Z, Claycomb JM.
Comparative functional characterization of the CSR-1 22G-RNA pathway in Caenorhabditis nematodes.
Nucleic Acids Res. 2015 43(1) 208-24 
[ PubMed ID = 25510497 ] [ RRCの論文情報 ]

Barberán-Soler S, Fontrodona L, Ribó A, Lamm AT, Iannone C, Cerón J, Lehner B, Valcárcel J.
Co-option of the piRNA pathway for germline-specific alternative splicing of C. elegans TOR.
Cell Rep 2014 8(6) 1609-16 
[ PubMed ID = 25220461 ] [ RRCの論文情報 ]

Kennedy LM, Grishok A.
Neuronal migration is regulated by endogenous RNAi and chromatin-binding factor ZFP-1/AF10 in Caenorhabditis elegans.
Genetics 2014 197(1) 207-20 
[ PubMed ID = 24558261 ] [ RRCの論文情報 ]

Cecere G, Hoersch S, O'Keeffe S, Sachidanandam R, Grishok A.
Global effects of the CSR-1 RNA interference pathway on the transcriptional landscape.
Nat. Struct. Mol. Biol. 2014 21(4) 358-65 
[ PubMed ID = 24681887 ] [ RRCの論文情報 ]

Goh WS, Seah JW, Harrison EJ, Chen C, Hammell CM, Hannon GJ.
A genome-wide RNAi screen identifies factors required for distinct stages of C. elegans piRNA biogenesis.
Genes Dev. 2014 28(7) 797-807 
[ PubMed ID = 24696458 ] [ RRCの論文情報 ]

Seth M, Shirayama M, Gu W, Ishidate T, Conte D Jr, Mello CC.
The C. elegans CSR-1 argonaute pathway counteracts epigenetic silencing to promote germline gene expression.
Dev. Cell 2013 27(6) 656-63 
[ PubMed ID = 24360782 ] [ RRCの論文情報 ]

Wedeles CJ, Wu MZ, Claycomb JM.
Protection of germline gene expression by the C. elegans Argonaute CSR-1.
Dev. Cell 2013 27(6) 664-71 
[ PubMed ID = 24360783 ] [ RRCの論文情報 ]

Conine CC, Moresco JJ, Gu W, Shirayama M, Conte D Jr, Yates JR 3rd, Mello CC.
Argonautes promote male fertility and provide a paternal memory of germline gene expression in C. elegans.
Cell 2013 155(7) 1532-44 
[ PubMed ID = 24360276 ] [ RRCの論文情報 ]

Hall SE, Chirn GW, Lau NC, Sengupta P.
RNAi pathways contribute to developmental history-dependent phenotypic plasticity in C. elegans.
RNA 2013 19(3) 306-19 
[ PubMed ID = 23329696 ] [ RRCの論文情報 ]

Avgousti DC, Palani S, Sherman Y, Grishok A.
CSR-1 RNAi pathway positively regulates histone expression in C. elegans.
EMBO J. 2012 31(19) 3821-32 
[ PubMed ID = 22863779 ] [ RRCの論文情報 ]

Maniar JM, Fire AZ.
EGO-1, a C. elegans RdRP, modulates gene expression via production of mRNA-templated short antisense RNAs.
Curr. Biol. 2011 21(6) 449-59 
[ PubMed ID = 21396820 ] [ RRCの論文情報 ]

Updike DL, Strome S.
A genomewide RNAi screen for genes that affect the stability, distribution and function of P granules in Caenorhabditis elegans.
Genetics 2009 183(4) 1397-419 
[ PubMed ID = 19805813 ] [ RRCの論文情報 ]

Claycomb JM, Batista PJ, Pang KM, Gu W, Vasale JJ, van Wolfswinkel JC, Chaves DA, Shirayama M, Mitani S, Ketting RF, Conte D Jr, Mello CC.
The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation.
Cell 2009 139(1) 123-34 
[ PubMed ID = 19804758 ] [ RRCの論文情報 ]

She X, Xu X, Fedotov A, Kelly WG, Maine EM.
Regulation of heterochromatin assembly on unpaired chromosomes during Caenorhabditis elegans meiosis by components of a small RNA-mediated pathway.
PLoS Genet. 2009 5(8) e1000624 
[ PubMed ID = 19714217 ] [ RRCの論文情報 ]