HOME MUTANTS PROMOTER SEARCH FAQ & CONTACT  
ミニアンケート集計結果はこちら     MUTANTS
キーワード検索
分離済み変異体
スクリーニング中変異体
  

分離済み変異体
変異体一覧
項目検索
分譲申し込み方法
MTA
技術的なコメント
論文情報登録

スクリーニング中変異体
進行状況
スクリーニング申し込み方法
スクリーニング申し込み

フィードバック
フィードバックの
お願い
 
 
 

Last Update
null

 
staff only
AVAILABLE MUTANTS (ISOLATED)
 変異体 To English >>
 
Record No. 597
対立遺伝子 tm597
Sequence Name C09G12.8
CGC Name ced-10
Worm Base 対立遺伝子 tm597
CGC Name ced-10
Sequence C09G12.8
表現型 lethal or sterile. Dr. M. Hengartner: engulfment defect., Dr. E. Lundquist: Genetics 172, 893-913 (2006).
変異部位 34879/34880-35491/35492 (612 bp deletion)
染色体 IV
遺伝子構造 complement(join(34079..34271, 34756..34941, 35209..35300, 36089..36193))
マップポジション -3.32
バランサ Not Yet Balanced
バランサマップポジション
プライマー配列 IntRev:GGTAAAACGTGTCTCCTGAT,ExtFwd:GGGTGGATAAGTAAGAAAAGTAT,ExtRev:GTGTCGTCGTTGGTGACGGA,IntFwd:CGAGTTTAAGATGAAAAATCGTT
変異体送付先
寄託者 Dr. S. Mitani/NBRP
文献  論文登録
Walck-Shannon E, Reiner D, Hardin J.
Polarized Rac-dependent protrusions drive epithelial intercalation in the embryonic epidermis of C. elegans.
Development 2015 142(20) 3549-60 
[ PubMed ID = 26395474 ] [ RRCの論文情報 ]

Doi M, Minematsu H, Kubota Y, Nishiwaki K, Miyamoto M.
The novel Rac effector RIN-1 regulates neuronal cell migration and axon pathfinding in C. elegans.
Development 2013 140(16) 3435-44 
[ PubMed ID = 23900541 ] [ RRCの論文情報 ]

Patel FB, Soto MC.
WAVE/SCAR promotes endocytosis and early endosome morphology in polarized C. elegans epithelia.
Dev. Biol. 2013 377(2) 319-32 
[ PubMed ID = 23510716 ] [ RRCの論文情報 ]

Alan JK, Lundquist EA.
Analysis of Rho GTPase function in axon pathfinding using Caenorhabditis elegans.
Methods Mol. Biol. 2012 827 339-58 
[ PubMed ID = 22144285 ] [ RRCの論文情報 ]

Demarco RS, Struckhoff EC, Lundquist EA.
The Rac GTP exchange factor TIAM-1 acts with CDC-42 and the guidance receptor UNC-40/DCC in neuronal protrusion and axon guidance.
PLoS Genet. 2012 8(4) e1002665 
[ PubMed ID = 22570618 ] [ RRCの論文情報 ]

Hsieh HH, Hsu TY, Jiang HS, Wu YC.
Integrin α PAT-2/CDC-42 signaling is required for muscle-mediated clearance of apoptotic cells in Caenorhabditis elegans.
PLoS Genet. 2012 8(5) e1002663 
[ PubMed ID = 22615577 ] [ RRCの論文情報 ]

Fleming T, Chien SC, Vanderzalm PJ, Dell M, Gavin MK, Forrester WC, Garriga G.
The role of C. elegans Ena/VASP homolog UNC-34 in neuronal polarity and motility.
Dev. Biol. 2010 344(1) 94-106 
[ PubMed ID = 20452341 ] [ RRCの論文情報 ]

Patel FB, Bernadskaya YY, Chen E, Jobanputra A, Pooladi Z, Freeman KL, Gally C, Mohler WA, Soto MC.
The WAVE/SCAR complex promotes polarized cell movements and actin enrichment in epithelia during C. elegans embryogenesis.
Dev. Biol. 2008 324(2) 297-309 
[ PubMed ID = 18938151 ] [ RRCの論文情報 ]

Shakir MA, Jiang K, Struckhoff EC, Demarco RS, Patel FB, Soto MC, Lundquist EA.
The Arp2/3 activators WAVE and WASP have distinct genetic interactions with Rac GTPases in Caenorhabditis elegans axon guidance.
Genetics 2008 179(4) 1957-71 
[ PubMed ID = 18689885 ] [ RRCの論文情報 ]

Shakir MA, Gill JS, Lundquist EA.
Interactions of UNC-34 Enabled with Rac GTPases and the NIK kinase MIG-15 in Caenorhabditis elegans axon pathfinding and neuronal migration.
Genetics 2006 172(2) 893-913 
[ PubMed ID = 16204220 ] [ RRCの論文情報 ]