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AVAILABLE MUTANTS (ISOLATED)
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Record No. 574
対立遺伝子 tm574
Sequence Name T07G12.10
CGC Name zim-2
Worm Base 対立遺伝子 tm574
CGC Name zim-2
Sequence T07G12.10
表現型 homozygous viable, Dr. A. Dernburg: Dev. Cell 11, 817 (2006). Dr. W. Hanna-Rose: Genetics 177, 1221 (2007).
変異部位 27386/27387-27801/27802 (415 bp deletion)
染色体 IV
遺伝子構造 join(27217..27315, 27378..28168, 28467..28746, 28819..29079, 29171..29364, 29416..29468, 29516..29592)
マップポジション 4.62
バランサ
バランサマップポジション
プライマー配列 ExtFwd:CGCCGTTTCATTTGGAACTT,ExtRev:TGTCGAGTTGTCTGGCATGA,IntFwd:GCTGCTGCCCATTTTCGATA,IntRev:GACAACGCGGCAAAACAACT
変異体送付先
寄託者 Dr. S. Mitani
文献  論文登録
Muscat CC, Torre-Santiago KM, Tran MV, Powers JA, Wignall SM.
Kinetochore-independent chromosome segregation driven by lateral microtubule bundles.
Elife 2015 4 e06462 
[ PubMed ID = 26026148 ] [ RRCの論文情報 ]

Leopold LE, Heestand BN, Seong S, Shtessel L, Ahmed S.
Lack of pairing during meiosis triggers multigenerational transgene silencing in Caenorhabditis elegans.
Proc. Natl. Acad. Sci. U.S.A. 2015 112(20) E2667-76 
[ PubMed ID = 25941370 ] [ RRCの論文情報 ]

Stamper EL, Rodenbusch SE, Rosu S, Ahringer J, Villeneuve AM, Dernburg AF.
Identification of DSB-1, a protein required for initiation of meiotic recombination in Caenorhabditis elegans, illuminates a crossover assurance checkpoint.
PLoS Genet. 2013 9(8) e1003679 
[ PubMed ID = 23990794 ] [ RRCの論文情報 ]

Checchi PM, Engebrecht J.
Caenorhabditis elegans histone methyltransferase MET-2 shields the male X chromosome from checkpoint machinery and mediates meiotic sex chromosome inactivation.
PLoS Genet. 2011 7(9) e1002267 
[ PubMed ID = 21909284 ] [ RRCの論文情報 ]

Jaramillo-Lambert A, Harigaya Y, Vitt J, Villeneuve A, Engebrecht J.
Meiotic errors activate checkpoints that improve gamete quality without triggering apoptosis in male germ cells.
Curr. Biol. 2010 20(23) 2078-89 
[ PubMed ID = 20970339 ] [ RRCの論文情報 ]

Bessler JB, Andersen EC, Villeneuve AM.
Differential localization and independent acquisition of the H3K9me2 and H3K9me3 chromatin modifications in the Caenorhabditis elegans adult germ line.
PLoS Genet. 2010 6(1) e1000830 
[ PubMed ID = 20107519 ] [ RRCの論文情報 ]

Jaramillo-Lambert A, Engebrecht J.
A single unpaired and transcriptionally silenced X chromosome locally precludes checkpoint signaling in the Caenorhabditis elegans germ line.
Genetics 2009 184(3) 613-28 
[ PubMed ID = 20008570 ] [ RRCの論文情報 ]

Gu SG, Fire A.
Partitioning the C. elegans genome by nucleosome modification, occupancy, and positioning.
Chromosoma 2009 119(1) 73-87 
[ PubMed ID = 19705140 ] [ RRCの論文情報 ]

Phillips CM, Meng X, Zhang L, Chretien JH, Urnov FD, Dernburg AF.
Identification of chromosome sequence motifs that mediate meiotic pairing and synapsis in C. elegans.
Nat. Cell Biol. 2009 11(8) 934-42 
[ PubMed ID = 19620970 ] [ RRCの論文情報 ]

Arur S, Ohmachi M, Nayak S, Hayes M, Miranda A, Hay A, Golden A, Schedl T.
Multiple ERK substrates execute single biological processes in Caenorhabditis elegans germ-line development.
Proc. Natl. Acad. Sci. U.S.A. 2009 106(12) 4776-81 
[ PubMed ID = 19264959 ] [ RRCの論文情報 ]

Sun H, Nelms BL, Sleiman SF, Chamberlin HM, Hanna-Rose W.
Modulation of Caenorhabditis elegans transcription factor activity by HIM-8 and the related Zinc-Finger ZIM proteins.
Genetics 2007 177(2) 1221-6 
[ PubMed ID = 17720937 ] [ RRCの論文情報 ]

Phillips CM, Dernburg AF.
A family of zinc-finger proteins is required for chromosome-specific pairing and synapsis during meiosis in C. elegans.
Dev. Cell 2006 11(6) 817-29 
[ PubMed ID = 17141157 ] [ RRCの論文情報 ]