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AVAILABLE MUTANTS (ISOLATED)
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Record No. 1860
対立遺伝子 tm1860
Sequence Name R09A1.1
CGC Name ergo-1
Worm Base 対立遺伝子 tm1860
CGC Name ergo-1
Sequence R09A1.1
表現型 homozygous viable. Dr. C. Mello, Cell 127, 747-457 (2006). Dr. R. Lu: PLoS Pathogens 5, e1000286 (2009).
変異部位 7750/7751-8908/8909 (1158 bp deletion)
染色体 V
遺伝子構造 join(5337..6277, 7119..7303, 8644..9562, 10623..10897, 11603..11682, 12892..13754, 14495..14597)
マップポジション -19.85
バランサ
バランサマップポジション
プライマー配列 ExtRev:GAGCGGCTGCTCAGAAGACT,IntFwd:ACCCGAGCTTCCGGATGTGT,IntRev:TCTCGGTGGATCATGAGTAA,ExtFwd:AAGCGTACGAACCCGAGCTT
変異体送付先
寄託者 Dr. S. Mitani
文献  論文登録
Palominos MF, Verdugo L, Gabaldon C, Pollak B, Ortíz-Severín J, Varas MA, Chávez FP, Calixto A.
Transgenerational Diapause as an Avoidance Strategy against Bacterial Pathogens in Caenorhabditis elegans.
MBio 2017 8(5)  
[ PubMed ID = 29018118 ] [ RRCの論文情報 ]

Von Stetina SE, Mango SE.
PAR-6, but not E-cadherin and β-integrin, is necessary for epithelial polarization in C. elegans.
Dev. Biol. 2015 403(1) 5-14 
[ PubMed ID = 25773364 ] [ RRCの論文情報 ]

Kennedy LM, Grishok A.
Neuronal migration is regulated by endogenous RNAi and chromatin-binding factor ZFP-1/AF10 in Caenorhabditis elegans.
Genetics 2014 197(1) 207-20 
[ PubMed ID = 24558261 ] [ RRCの論文情報 ]

Zhuang JJ, Banse SA, Hunter CP.
The nuclear argonaute NRDE-3 contributes to transitive RNAi in Caenorhabditis elegans.
Genetics 2013 194(1) 117-31 
[ PubMed ID = 23457236 ] [ RRCの論文情報 ]

Hall SE, Chirn GW, Lau NC, Sengupta P.
RNAi pathways contribute to developmental history-dependent phenotypic plasticity in C. elegans.
RNA 2013 19(3) 306-19 
[ PubMed ID = 23329696 ] [ RRCの論文情報 ]

Billi AC, Alessi AF, Khivansara V, Han T, Freeberg M, Mitani S, Kim JK.
The Caenorhabditis elegans HEN1 ortholog, HENN-1, methylates and stabilizes select subclasses of germline small RNAs.
PLoS Genet. 2012 8(4) e1002617 
[ PubMed ID = 22548001 ] [ RRCの論文情報 ]

Dennis S, Sheth U, Feldman JL, English KA, Priess JR.
C. elegans germ cells show temperature and age-dependent expression of Cer1, a Gypsy/Ty3-related retrotransposon.
PLoS Pathog. 2012 8(3) e1002591 
[ PubMed ID = 22479180 ] [ RRCの論文情報 ]

Massirer KB, Perez SG, Mondol V, Pasquinelli AE.
The miR-35-41 family of microRNAs regulates RNAi sensitivity in Caenorhabditis elegans.
PLoS Genet. 2012 8(3) e1002536 
[ PubMed ID = 22412382 ] [ RRCの論文情報 ]

Fischer SE, Montgomery TA, Zhang C, Fahlgren N, Breen PC, Hwang A, Sullivan CM, Carrington JC, Ruvkun G.
The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications.
PLoS Genet. 2011 7(11) e1002369 
[ PubMed ID = 22102828 ] [ RRCの論文情報 ]

Zhuang JJ, Hunter CP.
Tissue specificity of Caenorhabditis elegans enhanced RNA interference mutants.
Genetics 2011 188(1) 235-7 
[ PubMed ID = 21385728 ] [ RRCの論文情報 ]

Conine CC, Batista PJ, Gu W, Claycomb JM, Chaves DA, Shirayama M, Mello CC.
Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans.
Proc. Natl. Acad. Sci. U.S.A. 2010 107(8) 3588-93 
[ PubMed ID = 20133686 ] [ RRCの論文情報 ]

Vasale JJ, Gu W, Thivierge C, Batista PJ, Claycomb JM, Youngman EM, Duchaine TF, Mello CC, Conte D Jr.
Sequential rounds of RNA-dependent RNA transcription drive endogenous small-RNA biogenesis in the ERGO-1/Argonaute pathway.
Proc. Natl. Acad. Sci. U.S.A. 2010 107(8) 3582-7 
[ PubMed ID = 20133583 ] [ RRCの論文情報 ]

Han T, Manoharan AP, Harkins TT, Bouffard P, Fitzpatrick C, Chu DS, Thierry-Mieg D, Thierry-Mieg J, Kim JK.
26G endo-siRNAs regulate spermatogenic and zygotic gene expression in Caenorhabditis elegans.
Proc. Natl. Acad. Sci. U.S.A. 2009 106(44) 18674-9 
[ PubMed ID = 19846761 ] [ RRCの論文情報 ]

Pavelec DM, Lachowiec J, Duchaine TF, Smith HE, Kennedy S.
Requirement for the ERI/DICER complex in endogenous RNA interference and sperm development in Caenorhabditis elegans.
Genetics 2009 183(4) 1283-95 
[ PubMed ID = 19797044 ] [ RRCの論文情報 ]

Mets DG, Meyer BJ.
Condensins regulate meiotic DNA break distribution, thus crossover frequency, by controlling chromosome structure.
Cell 2009 139(1) 73-86 
[ PubMed ID = 19781752 ] [ RRCの論文情報 ]

Lu R, Yigit E, Li WX, Ding SW.
An RIG-I-Like RNA helicase mediates antiviral RNAi downstream of viral siRNA biogenesis in Caenorhabditis elegans.
PLoS Pathog. 2009 5(2) e1000286 
[ PubMed ID = 19197349 ] [ RRCの論文情報 ]

Yigit E, Batista PJ, Bei Y, Pang KM, Chen CC, Tolia NH, Joshua-Tor L, Mitani S, Simard MJ, Mello CC.
Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi.
Cell 2006 127(4) 747-57 
[ PubMed ID = 17110334 ] [ RRCの論文情報 ]