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AVAILABLE MUTANTS (ISOLATED)
 変異体 To English >>
 
Record No. 1200
対立遺伝子 tm1200
Sequence Name C16C10.3
CGC Name hrde-1
Worm Base 対立遺伝子 tm1200
CGC Name hrde-1
Sequence C16C10.3
表現型 homozygous viable. Dr. C. Mello, Cell 127, 747-457 (2006).
変異部位 32390/32391-32764/32765 (374 bp deletion)
染色体 III
遺伝子構造 complement(join(30115..30274, 30324..30514, 30560..31508, 31556..32080, 32130..33083, 33129..33339, 33391..33499))
マップポジション -3.71
バランサ
バランサマップポジション
プライマー配列 IntRev:CAACAGGATTCCCAAACGAG,ExtRev:CATGGCCGACTTGCTCGACA,IntFwd:ACGTTCGACTTACTCGGCCT,ExtFwd:TTGGACAGCTTGTCGCAGAA
変異体送付先
寄託者 Dr. S. Mitani
文献  論文登録
Devanapally S, Ravikumar S, Jose AM.
Double-stranded RNA made in C. elegans neurons can enter the germline and cause transgenerational gene silencing.
Proc. Natl. Acad. Sci. U.S.A. 2015 112(7) 2133-8 
[ PubMed ID = 25646479 ] [ RRCの論文情報 ]

Robert VJ, Mercier MG, Bedet C, Janczarski S, Merlet J, Garvis S, Ciosk R, Palladino F.
The SET-2/SET1 histone H3K4 methyltransferase maintains pluripotency in the Caenorhabditis elegans germline.
Cell Rep 2014 9(2) 443-50 
[ PubMed ID = 25310986 ] [ RRCの論文情報 ]

Rechavi O, Houri-Ze'evi L, Anava S, Goh WS, Kerk SY, Hannon GJ, Hobert O.
Starvation-induced transgenerational inheritance of small RNAs in C. elegans.
Cell 2014 158(2) 277-87 
[ PubMed ID = 25018105 ] [ RRCの論文情報 ]

Zhou X, Xu F, Mao H, Ji J, Yin M, Feng X, Guang S.
Nuclear RNAi contributes to the silencing of off-target genes and repetitive sequences in Caenorhabditis elegans.
Genetics 2014 197(1) 121-32 
[ PubMed ID = 24532782 ] [ RRCの論文情報 ]

de Albuquerque BF, Luteijn MJ, Cordeiro Rodrigues RJ, van Bergeijk P, Waaijers S, Kaaij LJ, Klein H, Boxem M, Ketting RF.
PID-1 is a novel factor that operates during 21U-RNA biogenesis in Caenorhabditis elegans.
Genes Dev. 2014 28(7) 683-8 
[ PubMed ID = 24696453 ] [ RRCの論文情報 ]

Ni JZ, Chen E, Gu SG.
Complex coding of endogenous siRNA, transcriptional silencing and H3K9 methylation on native targets of germline nuclear RNAi in C. elegans.
BMC Genomics 2014 15 1157 
[ PubMed ID = 25534009 ] [ RRCの論文情報 ]

Wedeles CJ, Wu MZ, Claycomb JM.
Protection of germline gene expression by the C. elegans Argonaute CSR-1.
Dev. Cell 2013 27(6) 664-71 
[ PubMed ID = 24360783 ] [ RRCの論文情報 ]

Hall SE, Chirn GW, Lau NC, Sengupta P.
RNAi pathways contribute to developmental history-dependent phenotypic plasticity in C. elegans.
RNA 2013 19(3) 306-19 
[ PubMed ID = 23329696 ] [ RRCの論文情報 ]

Buckley BA, Burkhart KB, Gu SG, Spracklin G, Kershner A, Fritz H, Kimble J, Fire A, Kennedy S.
A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality.
Nature 2012 489(7416) 447-51 
[ PubMed ID = 22810588 ] [ RRCの論文情報 ]

Luteijn MJ, van Bergeijk P, Kaaij LJ, Almeida MV, Roovers EF, Berezikov E, Ketting RF.
Extremely stable Piwi-induced gene silencing in Caenorhabditis elegans.
EMBO J. 2012 31(16) 3422-30 
[ PubMed ID = 22850670 ] [ RRCの論文情報 ]

Ashe A, Sapetschnig A, Weick EM, Mitchell J, Bagijn MP, Cording AC, Doebley AL, Goldstein LD, Lehrbach NJ, Le Pen J, Pintacuda G, Sakaguchi A, Sarkies P, Ahmed S, Miska EA.
piRNAs can trigger a multigenerational epigenetic memory in the germline of C. elegans.
Cell 2012 150(1) 88-99 
[ PubMed ID = 22738725 ] [ RRCの論文情報 ]

Shirayama M, Seth M, Lee HC, Gu W, Ishidate T, Conte D Jr, Mello CC.
piRNAs initiate an epigenetic memory of nonself RNA in the C. elegans germline.
Cell 2012 150(1) 65-77 
[ PubMed ID = 22738726 ] [ RRCの論文情報 ]

Wu X, Shi Z, Cui M, Han M, Ruvkun G.
Repression of germline RNAi pathways in somatic cells by retinoblastoma pathway chromatin complexes.
PLoS Genet. 2012 8(3) e1002542 
[ PubMed ID = 22412383 ] [ RRCの論文情報 ]