分離済み変異体

tm975

Allele Nametm975
BalanceCompleted
OutCrossNot Accepted
Sequence NameF08C6.1
Gene Nameadt-2
Worm BaseAllele Name tm975 (x1)
Gene Name adt-2
Sequence F08C6.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. A. Frand: molting defective.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 31989/31990-32464/32465 (475 bp deletion)
ChromosomeX
Putative gene structurejoin(28264..28302, 30717..30792, 30841..30914, 30960..31151, 31220..31474, 31519..31713, 31834..31952, 32009..32155, 32199..32327, 32536..32668, 33295..33394, 33576..33792, 33847..33958, 34005..34106, 34415..34698, 34748..34962, 35279..35415, 35468..35852, 36697..36848)
Map position-1.48
Balancer,tmC30[tmIs1247]
Map position of balancer
Sequence of primersExtFwd:GTACGCCGCTATCAGTAACT,ExtRev:CCCTCTCTACCGGTTTACCA,IntFwd:ACGGTCATTGATGACGGTGA,IntRev:CACACCGTCGAAGTGGACAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Fernando T, Flibotte S, Xiong S, Yin J, Yzeiraj E, Moerman DG, Meléndez A, Savage-Dunn C.
C. elegans ADAMTS ADT-2 regulates body size by modulating TGFβ signaling and cuticle collagen organization.
Dev Biol 2011 352(1) 92-103 
[ PubMed ID = 21256840 ] [ RRC reference ]