分離済み変異体

tm933

Allele Nametm933
BalanceNot Required
OutCrossNot Accepted
Sequence NameT10G3.5
Gene Nameeea-1
Worm BaseAllele Name tm933
Gene Name eea-1
Sequence T10G3.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. G. Hermann: WT gut granules. Dr. C. Rongo: Normal GLR-1::GFP localization. Dr. Z. Zhou: no persistent cell corpses.Dr. O. Blacque: WT dye-filling.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 26933/26934-27304/27305 (371 bp deletion)
ChromosomeV
Putative gene structurecomplement(join(22118..22373, 22936..23228, 23544..23807, 23855..24082, 24128..24457, 25478..26365, 26694..26768, 26863..27804, 27846..28019, 28076..28120))
Map position5.35
Balancer
Map position of balancer
Sequence of primersIntFwd:GCTTCAGCATCTCTCAGCTT,ExtFwd:CTTTGTCAGTCCTTGATGCT,IntRev:CTAAACAACAGTCGACCAAG,ExtRev:ATTTAGATTGACGGCCGACT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Lu N, Shen Q, Mahoney TR, Liu X, Zhou Z.
Three sorting nexins drive the degradation of apoptotic cells in response to PtdIns(3)P signaling.
Mol Biol Cell 2011 22(3) 354-74 
[ PubMed ID = 21148288 ] [ RRC reference ]

Hermann GJ, Schroeder LK, Hieb CA, Kershner AM, Rabbitts BM, Fonarev P, Grant BD, Priess JR.
Genetic analysis of lysosomal trafficking in Caenorhabditis elegans.
Mol Biol Cell 2005 16(7) 3273-88 
[ PubMed ID = 15843430 ] [ RRC reference ]