Home > 分離済み変異体 > tm843

分離済み変異体

Allele Name		tm843
Balance		Not Required
OutCross		Not Accepted
Sequence Name		C30H6.6
Gene Name		haf-1
Worm Base	Allele Name	tm843
	Gene Name	haf-1
	Sequence	C30H6.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		Homozygous viable. Dr. L. Timmons: negative for RNAi defects using various feeding strains to deliver dsRNA.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		25783/25784-26622/26623 (839 bp deletion)
Chromosome		IV
Putative gene structure		join(25559..25772, 25825..26162, 26211..26357, 26405..26486, 26531..27111, 27158..27357, 27401..27599)
Map position		16.59
Balancer
Map position of balancer
Sequence of primers		ExtFwd:GATTGTTAGCAATCGGTGCA,IntRev:GCCACAGGAGTATTTACTCT,IntFwd:CATTGGCTACAGCTGCGAAA,ExtRev:TAATGAAAATCCGCGAGCCA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Mao XR, Kaufman DM, Crowder CM. Nicotinamide mononucleotide adenylyltransferase promotes hypoxic survival by activating the mitochondrial unfolded protein response. Cell Death Dis 2016 7(2) e2113  [ PubMed ID = 26913604 ] [ RRC reference ] Kaufman DM, Crowder CM. Mitochondrial Proteostatic Collapse Leads to Hypoxic Injury. Curr Biol 2015 25(16) 2171-6  [ PubMed ID = 26234215 ] [ RRC reference ] C. elegans Deletion Mutant Consortium. large-scale screening for targeted knockouts in the Caenorhabditis elegans genome. G3 (Bethesda) 2012 2(11) 1415-25  [ PubMed ID = 23173093 ] [ RRC reference ] Haynes CM, Yang Y, Blais SP, Neubert TA, Ron D. The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans. Mol Cell 2010 37(4) 529-40  [ PubMed ID = 20188671 ] [ RRC reference ] Sundaram P, Han W, Cohen N, Echalier B, Albin J, Timmons L. Caenorhabditis elegans ABCRNAi transporters interact genetically with rde-2 and mut-7. Genetics 2008 178(2) 801-14  [ PubMed ID = 18245353 ] [ RRC reference ]