分離済み変異体

tm827

Allele Nametm827
BalanceNot Required
OutCrossNot Accepted
Sequence NameC36B1.12
Gene Nameimp-1
Worm BaseAllele Name tm827
Gene Name imp-1
Sequence C36B1.12
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" Homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 39986/39987-40268/40269 (282 bp deletion)
ChromosomeI
Putative gene structurejoin(38813..38869, 38915..39292, 39464..39553, 39597..39686, 39730..39884, 39938..40116, 40164..40301, 40352..40710, 40941..41055, 41106..41395, 41818..41925)
Map position3.05
Balancer
Map position of balancer
Sequence of primersIntRev:AGCAACGAGGTAGCCTGTAA,IntFwd:AGTTTTGGAACCATGGGTGT,ExtRev:CTCGTTCAGAGAATCCATTC,ExtFwd:GGAACGCGAGCCAGTTCACT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Grigorenko AP, Moliaka YK, Plotnikova OV, Smirnov A, Nikishina VA, Goltsov AY, Gusev F, Andreeva TV, Nelson O, Bezprozvanny I, Rogaev EI.
Mutational re-modeling of di-aspartyl intramembrane proteases: uncoupling physiologically-relevant activities from those associated with Alzheimer's disease.
Oncotarget 2017 8(47) 82006-82026 
[ PubMed ID = 29137240 ] [ RRC reference ]