分離済み変異体

tm808

Allele Nametm808
BalanceCompleted
OutCrossNot Accepted
Sequence NameF32D1.1
Gene Namefigl-1
Worm BaseAllele Name tm808 (x1)
Gene Name figl-1
Sequence F32D1.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" Lethal or sterile. Dr. T. Ogura: sterile. Dr. M. Peter: J. Cell Sci 120, 3179 (2007).
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 3063/3064-TA-4129/4130 (1066 bp deletion + 2 bp insertion)
ChromosomeV
Putative gene structurecomplement(join(128..265, 1137..1767, 2779..3210, 3914..4497))
Map position-5.91
Balancerunc-62(e644) V
Map position of balancer
Sequence of primersExtRev:TAGAACCGTTGATGTGTCGT,IntRev:AAACAAGACACCCGGAAGCT,ExtFwd:GCAGTACAACAATCTCCCGT,IntFwd:TTTTCGCTCCTTCCAATCCA
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Onitake A, Yamanaka K, Esaki M, Ogura T.
Caenorhabditis elegans fidgetin homolog FIGL-1, a nuclear-localized AAA ATPase, binds to SUMO.
J Struct Biol 2012 179(2) 143-51 
[ PubMed ID = 22575764 ] [ RRC reference ]

Luke-Glaser S, Pintard L, Tyers M, Peter M.
The AAA-ATPase FIGL-1 controls mitotic progression, and its levels are regulated by the CUL-3MEL-26 E3 ligase in the C. elegans germ line.
J Cell Sci 2007 120(Pt 18) 3179-87 
[ PubMed ID = 17878235 ] [ RRC reference ]