分離済み変異体

tm805

Allele Nametm805
BalanceNot Required
OutCrossNot Accepted
Sequence NameT22H2.5a
Gene Namescrm-1
Worm BaseAllele Name tm805
Gene Name scrm-1
Sequence T22H2.5a
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 1166/1167-ATAATAT-1735/1736 (569 bp deletion + 7 bp insertion)
ChromosomeI
Putative gene structurecomplement(join(772..776, 1008..1053, 1101..1159, 1206..1308, 1715..2017, 2118..2192))
Map position9.53
Balancer
Map position of balancer
Sequence of primersExtFwd:AACCATCGGGGCAGCAGCAT,IntFwd:GCGGAGCTTGCTGTACCTTT,IntRev:CACGGAGCAACAGAGCCCTA,ExtRev:GGTGCTCCACGGAAGCATGA
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Murari E, Meadows D, Cuda N, Mangone M.
A comprehensive analysis of 3'UTRs in Caenorhabditis elegans.
Nucleic Acids Res 2024 52(13) 7523-7538 
[ PubMed ID = 38917330 ] [ RRC reference ]

Weng Y, Murphy CT.
Male-specific behavioral and transcriptomic changes in aging C. elegans neurons.
iScience 2024 27(6) 109910 
[ PubMed ID = 38783998 ] [ RRC reference ]

Raiders S, Black EC, Bae A, MacFarlane S, Klein M, Shaham S, Singhvi A.
Glia actively sculpt sensory neurons by controlled phagocytosis to tune animal behavior.
Elife 2021 10  
[ PubMed ID = 33759761 ] [ RRC reference ]

Nichols ALA, Meelkop E, Linton C, Giordano-Santini R, Sullivan RK, Donato A, Nolan C, Hall DH, Xue D, Neumann B, Hilliard MA.
The Apoptotic Engulfment Machinery Regulates Axonal Degeneration in C. elegans Neurons.
Cell Rep 2016 14(7) 1673-1683 
[ PubMed ID = 26876181 ] [ RRC reference ]

Yu H, Aleman-Meza B, Gharib S, Labocha MK, Cronin CJ, Sternberg PW, Zhong W.
Systematic profiling of Caenorhabditis elegans locomotive behaviors reveals additional components in G-protein Gαq signaling.
Proc Natl Acad Sci U S A 2013 110(29) 11940-5 
[ PubMed ID = 23818641 ] [ RRC reference ]

Wang X, Wang J, Gengyo-Ando K, Gu L, Sun CL, Yang C, Shi Y, Kobayashi T, Shi Y, Mitani S, Xie XS, Xue D.
C. elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells through phospholipid scramblase SCRM-1.
Nat Cell Biol 2007 9(5) 541-9 
[ PubMed ID = 17401362 ] [ RRC reference ]