分離済み変異体

tm797

Allele Nametm797
Allele Type通常株
Sequence NameF11D5.3
Gene NameF11D5.3
Worm BaseAllele Name tm797
Gene Name F11D5.3
Sequence F11D5.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. T. Schedl: fertile, normal locomotion.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 19813/19814-20162/20163 (349 bp deletion)
ChromosomeX
Putative gene structurejoin(13790..13856, 16299..16404, 17621..17718, 17768..17901, 19471..19618, 19728..20017, 20062..20374, 20428..20695, 20915..20986, 21035..21261, 21311..21440, 21488..21565, 21894..22200, 22251..22406)
Map position-10.56
Balancer
Map position of balancer
Sequence of primersIntFwd:CGACATCTTGACCGGGCAAT,ExtFwd:GCTAATAATGACACGGAGCA,IntRev:CTTTCGAGCTACAGGTAAAG,ExtRev:GGAGCACTGGGAGTCTAGGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Shimizu T, Kato Y, Sakai Y, Hisamoto N, Matsumoto K.
N-Glycosylation of the Discoidin Domain Receptor Is Required for Axon Regeneration in Caenorhabditis elegans.
Genetics 2019 213(2) 491-500 
[ PubMed ID = 31371405 ] [ RRC reference ]

Hisamoto N, Nagamori Y, Shimizu T, Pastuhov SI, Matsumoto K.
The C. elegans Discoidin Domain Receptor DDR-2 Modulates the Met-like RTK-JNK Signaling Pathway in Axon Regeneration.
PLoS Genet 2016 12(12) e1006475 
[ PubMed ID = 27984580 ] [ RRC reference ]

Unsoeld T, Park JO, Hutter H.
Discoidin domain receptors guide axons along longitudinal tracts in C. elegans.
Dev Biol 2013 374(1) 142-52 
[ PubMed ID = 23147028 ] [ RRC reference ]