分離済み変異体

tm789

Allele Nametm789
BalanceNot Required
OutCrossNot Accepted
Sequence NameW02A2.1
Gene Namefat-2
Worm BaseAllele Name tm789
Gene Name fat-2
Sequence W02A2.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. K. Sakamoto: J. Biochem 144, 149 (2008). Dr. S. Boulton: does not interact with brc-1 (tm1145) or brd-1 (dw1).
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 1701/1702-2107/2108 (406 bp deletion)
ChromosomeIV
Putative gene structurejoin(830..1480, 2149..2274, 2875..3228)
Map position8.53
Balancer
Map position of balancer
Sequence of primersExtFwd:GTGATGTGATGCTGGGAAGT,IntRev:TCTCACTCCCTAACTCGGAA,IntFwd:GCATACATTGGCCCAATGCA,ExtRev:AACACGGCTCCCACTCGCTT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Chamoli M, Goyala A, Tabrez SS, Siddiqui AA, Singh A, Antebi A, Lithgow GJ, Watts JL, Mukhopadhyay A.
Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction.
Nat Commun 2020 11(1) 4865 
[ PubMed ID = 32978396 ] [ RRC reference ]

Horikawa M, Sakamoto K.
Polyunsaturated fatty acids are involved in regulatory mechanism of fatty acid homeostasis via daf-2/insulin signaling in Caenorhabditis elegans.
Mol Cell Endocrinol 2010 323(2) 183-92 
[ PubMed ID = 20226839 ] [ RRC reference ]