分離済み変異体

tm781

Allele Nametm781
BalanceCompleted
OutCrossNot Accepted
Sequence NameF42A6.7
Gene Namehrp-1
Worm BaseAllele Name tm781 (x1)
Gene Name hrp-1
Sequence F42A6.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 18690/18691-19073/19074 (383 bp deletion)
ChromosomeIV
Putative gene structurecomplement(join(17860..18137, 18190..18925, 19006..19032))
Map position-4.68
Balancer,tmC25[tmIs1241]
Map position of balancer
Sequence of primersExtFwd:TATCGGAGACCGGCACCACT,IntFwd:TCCCTGAGACAATGACTCCA,ExtRev:GCGTCGCGTGTAACCCTTTT,IntRev:CTCTGTGGTTTTCGAGAGCA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Eck RJ, Stair JG, Kraemer BC, Liachko NF.
Simple models to understand complex disease: 10 years of progress from Caenorhabditis elegans models of amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Front Neurosci 2023 17 1300705 
[ PubMed ID = 38239833 ] [ RRC reference ]

Ryan VH, Perdikari TM, Naik MT, Saueressig CF, Lins J, Dignon GL, Mittal J, Hart AC, Fawzi NL.
Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration.
EMBO J 2021 40(3) e105001 
[ PubMed ID = 33349959 ] [ RRC reference ]