分離済み変異体

tm773

Allele Nametm773
BalanceNot Required
OutCrossNot Accepted
Sequence NameF32G8.6
Gene Namecat-4
Worm BaseAllele Name tm773
Gene Name cat-4
Sequence F32G8.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 17232/17233-17882/17883 (650 bp deletion)
ChromosomeV
Putative gene structurejoin(17476..17638, 18206..18301, 18349..18546, 18605..18819)
Map position2.6
Balancer
Map position of balancer
Sequence of primersExtFwd:GAAGGAATGGCGGAAAACGA,ExtRev:GTGGTGGAAGCATTGATCTT,IntRev:CCATACACATGTGACTAGCT,IntFwd:GATGTATGGGACGACGTCTT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Hernandez-Lima MA, Seo B, Urban ND, Truttmann MC.
Modulation of C. elegans behavior, fitness, and lifespan by AWB/ASH-dependent death perception.
Curr Biol 2025 35(9) 2128-2138.e6 
[ PubMed ID = 40250434 ] [ RRC reference ]

Hernandez-Lima MA, Seo B, Urban ND, Truttmann MC.
C. elegans behavior, fitness, and lifespan, are modulated by AWB/ASH-dependent death perception.
bioRxiv 2024   
[ PubMed ID = 39416137 ] [ RRC reference ]

Chuang M, Hsiao TI, Tong A, Xu S, Chisholm AD.
DAPK interacts with Patronin and the microtubule cytoskeleton in epidermal development and wound repair.
Elife 2016 5  
[ PubMed ID = 27661253 ] [ RRC reference ]

Loer CM, Calvo AC, Watschinger K, Werner-Felmayer G, O'Rourke D, Stroud D, Tong A, Gotenstein JR, Chisholm AD, Hodgkin J, Werner ER, Martinez A.
Cuticle integrity and biogenic amine synthesis in Caenorhabditis elegans require the cofactor tetrahydrobiopterin (BH4).
Genetics 2015 200(1) 237-53 
[ PubMed ID = 25808955 ] [ RRC reference ]

Baker RH, Britton C, Roberts B, Loer CM, Matthews JB, Nisbet AJ.
Melanisation of Teladorsagia circumcincta larvae exposed to sunlight: a role for GTP-cyclohydrolase in nematode survival.
Int J Parasitol 2012 42(10) 887-91 
[ PubMed ID = 22884628 ] [ RRC reference ]