Home > 分離済み変異体 > tm761

分離済み変異体

Allele Name		tm761
Allele Type		バランス済
Sequence Name		C16C2.2
Gene Name		eat-16
Worm Base	Allele Name	tm761
	Gene Name	eat-16
	Sequence	C16C2.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile. Dr. R. Horvitz: could not recover mutants from heterozygotes.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		10793/10794-AAAAATTTGGTTTTTA-12018/12019 (1225 bp deletion + 16 bp insertion)
Chromosome		I
Putative gene structure		join(9906..9926, 9977..10096, 10207..10290, 10355..10448, 10493..10571, 10949..11245, 11383..11496, 11544..12054, 12101..12186, 12504..12519)
Map position		3.87
Balancer		hT2 bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primers		IntFwd:CAGCAATTGATAGCTCTCGT,ExtFwd:CCTCATGCCATCACCGGTCA,ExtRev:ACTTGACCCCATGAGCCTGT,IntRev:TGGCAGCGAGTCGGACGATA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Dhakal P, Chaudhry SI, Signorelli R, Collins KM. Serotonin signals through postsynaptic Gαq, Trio RhoGEF, and diacylglycerol to promote Caenorhabditis elegans egg-laying circuit activity and behavior. Genetics 2022 221(3)   [ PubMed ID = 35579369 ] [ RRC reference ] Huang H, Zhu CT, Skuja LL, Hayden DJ, Hart AC. Genome-Wide Screen for Genes Involved in Caenorhabditis elegans Developmentally Timed Sleep. G3 (Bethesda) 2017 7(9) 2907-2917  [ PubMed ID = 28743807 ] [ RRC reference ] Porter MY, Koelle MR. RSBP-1 is a membrane-targeting subunit required by the Galpha(q)-specific but not the Galpha(o)-specific R7 regulator of G protein signaling in Caenorhabditis elegans. Mol Biol Cell 2010 21(2) 232-43  [ PubMed ID = 19923320 ] [ RRC reference ] Porter MY, Xie K, Pozharski E, Koelle MR, Martemyanov KA. A conserved protein interaction interface on the type 5 G protein beta subunit controls proteolytic stability and activity of R7 family regulator of G protein signaling proteins. J Biol Chem 2010 285(52) 41100-12  [ PubMed ID = 20959458 ] [ RRC reference ] Krzyzanowski MC, Brueggemann C, Ezak MJ, Wood JF, Michaels KL, Jackson CA, Juang BT, Collins KD, Yu MC, L'etoile ND, Ferkey DM. The C. elegans cGMP-dependent protein kinase EGL-4 regulates nociceptive behavioral sensitivity. PLoS Genet 2013 9(7) e1003619  [ PubMed ID = 23874221 ] [ RRC reference ]