分離済み変異体

tm753

Allele Nametm753
BalanceNot Required
OutCrossNot Accepted
Sequence NameF31B12.1
Gene Nameplc-1
Worm BaseAllele Name tm753
Gene Name plc-1
Sequence F31B12.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. V. Maricq: reduced brood size that is a likely result of faulty spermatheca dilation. Dr. H. Baylis: PLoS Genetics 4, e1000043 (2008).
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 11944/11955-12432/12433 (478 bp deletion)
ChromosomeX
Putative gene structurecomplement(join(28188..28492, 28951..[F31B12]154, 438..576, 679..806, 861..1047, 1702..1788, 1907..2143, 2194..2290, 2544..2875, 2924..3196, 3570..3869, 3914..4066, 4114..4339, 4654..4759, 4804..5041, 5122..5232, 6422..6649, 9135..9255, 9692..9785, 9834..9973, 10132..10345, 10499..10764, 10993..11071, 11463..11601, 11651..11800, 11849..12031, 12155..12390, 12561..12686, 12731..13022, 13143..13352, 13413..13693, 15958..16071)
Map position2.54
Balancer
Map position of balancer
Sequence of primersExtFwd:CAGCAAATAGCCTGGAGAGT,IntFwd:GGCGGACCAGATTGTGACGA,IntRev:CACAATCTCGTGTGATTCCA,ExtRev:AACGAGCACTGAGAATGCCA
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Nagy AI, Vázquez-Manrique RP, Lopez M, Christov CP, Sequedo MD, Herzog M, Herlihy AE, Bodak M, Gatsi R, Baylis HA.
IP3 signalling regulates exogenous RNAi in Caenorhabditis elegans.
EMBO Rep 2015 16(3) 341-50 
[ PubMed ID = 25608529 ] [ RRC reference ]

Kunitomo H, Sato H, Iwata R, Satoh Y, Ohno H, Yamada K, Iino Y.
Concentration memory-dependent synaptic plasticity of a taste circuit regulates salt concentration chemotaxis in Caenorhabditis elegans.
Nat Commun 2013 4 2210 
[ PubMed ID = 23887678 ] [ RRC reference ]

Kimata T, Tanizawa Y, Can Y, Ikeda S, Kuhara A, Mori I.
Synaptic polarity depends on phosphatidylinositol signaling regulated by myo-inositol monophosphatase in Caenorhabditis elegans.
Genetics 2012 191(2) 509-21 
[ PubMed ID = 22446320 ] [ RRC reference ]

Vázquez-Manrique RP, Nagy AI, Legg JC, Bales OA, Ly S, Baylis HA.
Phospholipase C-epsilon regulates epidermal morphogenesis in Caenorhabditis elegans.
PLoS Genet 2008 4(3) e1000043 
[ PubMed ID = 18369461 ] [ RRC reference ]