Home > 分離済み変異体 > tm750

分離済み変異体

Allele Name		tm750
Balance		Not Required
OutCross		Not Accepted
Sequence Name		C07H6.1
Gene Name		lig-4
Worm Base	Allele Name	tm750
	Gene Name	lig-4
	Sequence	C07H6.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. S. Ahmed: Genetics 173, 1301-1317 (2006). Dr. J-L. Bessereau: EMBO J. 26, 170 (2007). Dr. H-S. Koo: the germ cells are slightly (10%) resistent to ionizing radiation (gamma rays) and DNA crosslinking.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		38120/38121-39372/39373 (1252 bp deletion)
Chromosome		III
Putative gene structure		join(37728..37848, 37901..38200, 38248..38561, 38611..38733, 38996..39209, 39255..39405, 39456..39551, 39601..40012, 40099..40213, 40261..40407, 40774..40970)
Map position		-0.7
Balancer
Map position of balancer
Sequence of primers		ExtRev:ATTTGGCACGTTTCAGACGA,ExtFwd:AGTTCGACATGGGACCGACT,IntFwd:GTTGGCAAGCTTTATGGCAA,IntRev:CGAACAGGAGCTGCTGTAAA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Suehiro Y, Yoshina S, Motohashi T, Iwata S, Dejima K, Mitani S. Efficient collection of a large number of mutations by mutagenesis of DNA damage response defective animals. Sci Rep 2021 11(1) 7630  [ PubMed ID = 33828169 ] [ RRC reference ] Dejima K, Hori S, Iwata S, Suehiro Y, Yoshina S, Motohashi T, Mitani S. An Aneuploidy-Free and Structurally Defined Balancer Chromosome Toolkit for Caenorhabditis elegans. Cell Rep 2018 22(1) 232-241  [ PubMed ID = 29298424 ] [ RRC reference ] Mateo AR, Kessler Z, Jolliffe AK, McGovern O, Yu B, Nicolucci A, Yanowitz JL, Derry WB. The p53-like Protein CEP-1 Is Required for Meiotic Fidelity in C. elegans. Curr Biol 2016 26(9) 1148-58  [ PubMed ID = 27151662 ] [ RRC reference ] Lowden MR, Meier B, Lee TW, Hall J, Ahmed S. End joining at Caenorhabditis elegans telomeres. Genetics 2008 180(2) 741-54  [ PubMed ID = 18780750 ] [ RRC reference ] Robert V, Bessereau JL. Targeted engineering of the Caenorhabditis elegans genome following Mos1-triggered chromosomal breaks. EMBO J 2007 26(1) 170-83  [ PubMed ID = 17159906 ] [ RRC reference ] Clejan I, Boerckel J, Ahmed S. Developmental modulation of nonhomologous end joining in Caenorhabditis elegans. Genetics 2006 173(3) 1301-17  [ PubMed ID = 16702421 ] [ RRC reference ]