分離済み変異体

tm745

Allele Nametm745
BalanceNot Required
OutCrossNot Accepted
Sequence NameF42G8.4
Gene Namepmk-3
Worm BaseAllele Name tm745
Gene Name pmk-3
Sequence F42G8.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. M. Hengartner: normal growth and progeny size, a slight increase in germline apoptosis. Dr. P. Sengupta: normal dye filling.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 25489/25490-26222/26223 (733 bp deletion)
ChromosomeIV
Putative gene structurejoin(24554..24805, 25289..25434, 25485..25569, 25868..25977, 26023..26170, 26344..26950, 27032..27108)
Map position3.63
Balancer
Map position of balancer
Sequence of primersExtFwd:TCGCTTGAGTGTTCGAGTTT,ExtRev:ATCATCGGTCAACGCGAGAT,IntRev:CTGGTTTCAAGTCACGATGT,IntFwd:CATGGCGTGTTTCGCAATAA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Guan L, Zhan Z, Yang Y, Miao Y, Huang X, Ding M.
Alleviating chronic ER stress by p38-Ire1-Xbp1 pathway and insulin-associated autophagy in C. elegans neurons.
PLoS Genet 2020 16(9) e1008704 
[ PubMed ID = 32986702 ] [ RRC reference ]

Noblett N, Wu Z, Ding ZH, Park S, Roenspies T, Flibotte S, Chisholm AD, Jin Y, Colavita A.
DIP-2 suppresses ectopic neurite sprouting and axonal regeneration in mature neurons.
J Cell Biol 2019 218(1) 125-133 
[ PubMed ID = 30396999 ] [ RRC reference ]

Laurent P, Ch'ng Q, Jospin M, Chen C, Lorenzo R, de Bono M.
Genetic dissection of neuropeptide cell biology at high and low activity in a defined sensory neuron.
Proc Natl Acad Sci U S A 2018 115(29) E6890-E6899 
[ PubMed ID = 29959203 ] [ RRC reference ]