分離済み変異体

tm731

Allele Nametm731
BalanceNot Required
OutCrossNot Accepted
Sequence NameF56F11.3
Gene Nameklf-1
Worm BaseAllele Name tm731
Gene Name klf-1
Sequence F56F11.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 26137/26138-26480/26481 (343 bp deletion)
ChromosomeIII
Putative gene structurejoin(24132..24267, 24829..25001, 25915..26107, 26901..26981, 27567..27863, 28534..28971, 29334..29423, 29578..29663)
Map position-9.93
Balancer
Map position of balancer
Sequence of primersIntFwd:AATGACCGTCTGGAACAGAT,ExtFwd:ACTCAACTCAGAGCCTTTTC,ExtRev:TCGGACTATCCATGTCAGCA,IntRev:GCATCCTCCACAACAATACT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Hsieh PN, Zhou G, Yuan Y, Zhang R, Prosdocimo DA, Sangwung P, Borton AH, Boriushkin E, Hamik A, Fujioka H, Fealy CE, Kirwan JP, Peters M, Lu Y, Liao X, Ramírez-Bergeron D, Feng Z, Jain MK.
A conserved KLF-autophagy pathway modulates nematode lifespan and mammalian age-associated vascular dysfunction.
Nat Commun 2017 8(1) 914 
[ PubMed ID = 29030550 ] [ RRC reference ]

Carrano AC, Dillin A, Hunter T.
A Krüppel-like factor downstream of the E3 ligase WWP-1 mediates dietary-restriction-induced longevity in Caenorhabditis elegans.
Nat Commun 2014 5 3772 
[ PubMed ID = 24805825 ] [ RRC reference ]