分離済み変異体

tm726

Allele Nametm726
BalanceCompleted
OutCrossNot Accepted
Sequence NameC02B8.4
Gene Namehlh-8
Worm BaseAllele Name tm726 (x1)
Gene Name hlh-8
Sequence C02B8.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 5378/5379-6024/6025 (646 deletion)
ChromosomeX
Putative gene structurejoin(3906..4007, 6027..6143, 6191..6338, 7054..7140, 7292..7374)
Map position-0.53
BalancertmC30[tmIs1247]
Map position of balancer
Sequence of primersIntRev:GGAGGGGGAATATGTGCTGA,IntFwd:CGTTCCCAAGCCATATCTCA,ExtFwd:GACTCTTTCGCATATCGCAT,ExtRev:GTGGAGGAATGCTGGATGGA
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Baccas M, Ganesan V, Leung A, Pineiro LR, McKillop AN, Liu J.
SEM-2/SoxC regulates multiple aspects of C. elegans postembryonic mesoderm development.
PLoS Genet 2025 21(1) e1011361 
[ PubMed ID = 39836649 ] [ RRC reference ]

Baccas M, Ganesan V, Leung A, Pineiro L, McKillop AN, Liu J.
SEM-2/SoxC regulates multiple aspects of C. elegans postembryonic mesoderm development.
bioRxiv 2024   
[ PubMed ID = 39005444 ] [ RRC reference ]

Meyers SG, Corsi AK.
C. elegans twist gene expression in differentiated cell types is controlled by autoregulation through intron elements.
Dev Biol 2010 346(2) 224-36 
[ PubMed ID = 20691175 ] [ RRC reference ]