分離済み変異体

tm725

Allele Nametm725
BalanceNot Required
OutCrossNot Accepted
Sequence NameY116A8C.36
Gene Nameitsn-1
Worm BaseAllele Name tm725
Gene Name itsn-1
Sequence Y116A8C.36
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. A. Salcini: aldicarb hypersensitive.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 220089/220090-220937/220938 (848 bp deletion)
ChromosomeIV
Putative gene structurejoin(219591..219740, 219792..220376, 220860..221357, 221469..221693, 221740..222370, 223152..223522, 224109..224425, 225326..225842)
Map position16.22
Balancer
Map position of balancer
Sequence of primersExtFwd:CGGTCACTGCACGAAATGCA,IntFwd:GCACTAATGCGCAGCAATCT,IntRev:TGAGCTGGCGCCTGAGCAAT,ExtRev:TGATCAACAGCACCCTTCGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Wang W, Bouhours M, Gracheva EO, Liao EH, Xu K, Sengar AS, Xin X, Roder J, Boone C, Richmond JE, Zhen M, Egan SE.
ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1.
Traffic 2008 9(5) 742-54 
[ PubMed ID = 18298590 ] [ RRC reference ]

Rose S, Malabarba MG, Krag C, Schultz A, Tsushima H, Di Fiore PP, Salcini AE.
Caenorhabditis elegans intersectin: a synaptic protein regulating neurotransmission.
Mol Biol Cell 2007 18(12) 5091-9 
[ PubMed ID = 17942601 ] [ RRC reference ]