Home > 分離済み変異体 > tm724

分離済み変異体

Allele Name		tm724
Balance		Completed
OutCross		Not Accepted
Sequence Name		C06A5.7
Gene Name		unc-94
Worm Base	Allele Name	tm724 (x1)
	Gene Name	unc-94
	Sequence	C06A5.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		15952/15953-AAAAAAAAAAAAATNGG-16637/16638 (685 bp deletion + 17 bp insertion)
Chromosome		I
Putative gene structure		complement(join(12870..12895, 13951..14098, 14822..14965, 15131..15226, 15281..15347, 15555..15717, 15799..16120, 16964..16972))
Map position		0.66
Balancer		hT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primers		IntRev:CCACCATTGGGATTGCTGTT,ExtRev:TTGAAGAGAGACCACCCCCA,IntFwd:GGCGAGCACTTGTTAGGTAA,ExtFwd:CTCATATGACACCACGGCGA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Cox-Paulson E, Cannataro V, Gallagher T, Hoffman C, Mantione G, Mcintosh M, Silva M, Vissichelli N, Walker R, Simske J, Ono S, Hoops H. The minus-end actin capping protein, UNC-94/tropomodulin, regulates development of the Caenorhabditis elegans intestine. Dev Dyn 2014 243(6) 753-64  [ PubMed ID = 24677443 ] [ RRC reference ] Cox-Paulson EA, Walck-Shannon E, Lynch AM, Yamashiro S, Zaidel-Bar R, Eno CC, Ono S, Hardin J. Tropomodulin protects α-catenin-dependent junctional-actin networks under stress during epithelial morphogenesis. Curr Biol 2012 22(16) 1500-5  [ PubMed ID = 22771044 ] [ RRC reference ] Yamashiro S, Cox EA, Baillie DL, Hardin JD, Ono S. Sarcomeric actin organization is synergistically promoted by tropomodulin, ADF/cofilin, AIP1 and profilin in C. elegans. J Cell Sci 2008 121(Pt 23) 3867-77  [ PubMed ID = 18984629 ] [ RRC reference ]