分離済み変異体

tm722

Allele Nametm722
BalanceCompleted
OutCrossNot Accepted
Sequence NameW02B12.3
Gene Namersp-1
Worm BaseAllele Name tm722 (x1)
Gene Name rsp-1
Sequence W02B12.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. M. Han: early larval lethal. Dr. P. Sengupta: Dyf+ in all sensory neurons.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 8529/8530-A-9936/9937 (1407 bp deletion + 1 bp insertion)
ChromosomeII
Putative gene structurejoin(9070..9192, 9246..9478, 9530..9602, 10114..10187, 10240..10530, 10578..10722)
Map position3.47
BalancerhT2,mIn1 [e128 mIs14]
Map position of balancer
Sequence of primersIntFwd:GCGTAGGTGTTCAGGTTGAT,ExtFwd:CATTGAATTTCGCCTGCGTA,IntRev:TGGAGATGGAGAGCGATCGA,ExtRev:ATCCCTTTTCCGAAGGCGAA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Galvin BD, Denning DP, Horvitz HR.
SPK-1, an SR protein kinase, inhibits programmed cell death in Caenorhabditis elegans.
Proc Natl Acad Sci U S A 2011 108(5) 1998-2003 
[ PubMed ID = 21245325 ] [ RRC reference ]