分離済み変異体

tm721

Allele Nametm721
BalanceCompleted
OutCrossNot Accepted
Sequence NameF23F12.9
Gene Namezip-8
Worm BaseAllele Name tm721 (x1)
Gene Name zip-8
Sequence F23F12.9
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. C. Kenyon: lethal and could not examine life span. Dr. I. Mori: thermotaxis assay impossible.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 3427/3428-A-5017/5018 (1590 bp deletion + 1 bp insertion)
ChromosomeIII
Putative gene structurejoin(3235..3326, 4490..4597, 4821..5010, 5061..5201)
Map position-1.2
BalancerhT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersIntRev:TGTCCCGTTGCAATATAGCC,ExtFwd:TTCCCAGCGGGTGTTCTCTG,IntFwd:TCCCAAAACTTCTCGGGTGG,ExtRev:CCTACTGTGTCCAAGCTTTA
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Tuckowski AM, Beydoun S, Kitto ES, Bhat A, Howington MB, Sridhar A, Bhandari M, Chambers K, Leiser SF.
fmo-4 promotes longevity and stress resistance via ER to mitochondria calcium regulation in C. elegans.
Elife 2025 13  
[ PubMed ID = 39951337 ] [ RRC reference ]

Murari E, Meadows D, Cuda N, Mangone M.
A comprehensive analysis of 3'UTRs in Caenorhabditis elegans.
Nucleic Acids Res 2024 52(13) 7523-7538 
[ PubMed ID = 38917330 ] [ RRC reference ]

Weng Y, Murphy CT.
Male-specific behavioral and transcriptomic changes in aging C. elegans neurons.
iScience 2024 27(6) 109910 
[ PubMed ID = 38783998 ] [ RRC reference ]