分離済み変異体

tm703

Allele Nametm703
Allele Type通常株
Sequence NameC24F3.5
Gene Nameabt-1
Worm BaseAllele Name tm703
Gene Name abt-1
Sequence C24F3.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 1128/1129-TGCCCACGTTACC-2109/2110 (981 bp deletion + 14 bp insertion)
ChromosomeIV
Putative gene structurecomplement(join(37430..37570, 38124..38544, 38729..[T17B5]209, 258..647, 691..806, 861..969, 1022..1202, 1250..1395, 1566..1674, 1725..1836, 1885..2013, 2058..2192, 2239..2397, 2440..2510, 2654..2752, 2796..2972, 3016..3132, 3179..3412, 3682..[C24F3]119, 168..288, 336..452, 496..585, 1289..1478, 1526..1607, 1656..1800, 2481..2567, 2989..3081, 3124..3186))
Map position4.56
Balancer
Map position of balancer
Sequence of primersIntFwd:CAATGAGACGAGAGCATATG,IntRev:CAGGCACTTACAATTAGGCA,ExtFwd:GTAACCACTGCTTCTGTCGT,ExtRev:TCAGGTGTGGCAAACCGGAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Levitte S, Salesky R, King B, Coe Smith S, Depper M, Cole M, Hermann GJ.
A Caenorhabditis elegans model of orotic aciduria reveals enlarged lysosome-related organelles in embryos lacking umps-1 function.
FEBS J 2010 277(6) 1420-39 
[ PubMed ID = 20148972 ] [ RRC reference ]

C. elegans Deletion Mutant Consortium.
large-scale screening for targeted knockouts in the Caenorhabditis elegans genome.
G3 (Bethesda) 2012 2(11) 1415-25 
[ PubMed ID = 23173093 ] [ RRC reference ]

Sundaram P, Han W, Cohen N, Echalier B, Albin J, Timmons L.
Caenorhabditis elegans ABCRNAi transporters interact genetically with rde-2 and mut-7.
Genetics 2008 178(2) 801-14 
[ PubMed ID = 18245353 ] [ RRC reference ]

Sundaram P, Echalier B, Han W, Hull D, Timmons L.
ATP-binding cassette transporters are required for efficient RNA interference in Caenorhabditis elegans.
Mol Biol Cell 2006 17(8) 3678-88 
[ PubMed ID = 16723499 ] [ RRC reference ]