Home > 分離済み変異体 > tm683

分離済み変異体

Allele Name		tm683
Allele Type		通常株
Sequence Name		C24B5.2
Gene Name		spas-1
Worm Base	Allele Name	tm683
	Gene Name	spas-1
	Sequence	C24B5.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		9170/9171-10087/10088 (917 bp deletion)
Chromosome		V
Putative gene structure		join(8325..8445, 8501..8683, 8739..8848, 8942..9124, 9225..9314, 9362..9686, 9735..10023, 10071..10209, 10256..10354)
Map position		1.95
Balancer
Map position of balancer
Sequence of primers		IntFwd:AGTGCGTCAACACTAACCTT,ExtRev:GTCATGCTAAGCTTCGATCT,IntRev:GTCGATTTCACGAATCGGAA,ExtFwd:TTGCGCAATTCTTGTCGACA
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication McDiarmid TA, Belmadani M, Liang J, Meili F, Mathews EA, Mullen GP, Hendi A, Wong WR, Rand JB, Mizumoto K, Haas K, Pavlidis P, Rankin CH. Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation. Proc Natl Acad Sci U S A 2020 117(1) 656-667  [ PubMed ID = 31754030 ] [ RRC reference ] Liu X, Guo X, Niu L, Li X, Sun F, Hu J, Wang X, Shen K. Atlastin-1 regulates morphology and function of endoplasmic reticulum in dendrites. Nat Commun 2019 10(1) 568  [ PubMed ID = 30718476 ] [ RRC reference ] Chuang M, Hsiao TI, Tong A, Xu S, Chisholm AD. DAPK interacts with Patronin and the microtubule cytoskeleton in epidermal development and wound repair. Elife 2016 5   [ PubMed ID = 27661253 ] [ RRC reference ] Julien C, Lissouba A, Madabattula S, Fardghassemi Y, Rosenfelt C, Androschuk A, Strautman J, Wong C, Bysice A, O'sullivan J, Rouleau GA, Drapeau P, Parker JA, Bolduc FV. Conserved pharmacological rescue of hereditary spastic paraplegia-related phenotypes across model organisms. Hum Mol Genet 2016 25(6) 1088-99  [ PubMed ID = 26744324 ] [ RRC reference ] Matsushita-Ishiodori Y, Yamanaka K, Ogura T. The C. elegans homologue of the spastic paraplegia protein, spastin, disassembles microtubules. Biochem Biophys Res Commun 2007 359(1) 157-62  [ PubMed ID = 17531954 ] [ RRC reference ]