分離済み変異体

tm6748

Allele Nametm6748
BalanceNot Required
OutCrossNot Accepted
Sequence NameB0336.5
Gene NameB0336.5
Worm BaseAllele Name tm6748
Gene Name B0336.5
Sequence B0336.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 6556/6557-6784/6785 (228 bp deletion)
ChromosomeIII
Putative gene structurejoin(5991..6047, 6096..6191, 6241..6556, 6631..6767)
Map position-1.45
Balancer
Map position of balancer
Sequence of primersIntRev:GGTAAAGAGCGTATGACGAC,IntFwd:GCGCTTTTTCGCAAGTGGTA,ExtRev:AGTGCCTGACCCAGTGTGGT,ExtFwd:ATTAATGAGGGCGTGGTCAC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Delaney CE, Methot SP, Kalck V, Seebacher J, Hess D, Gasser SM, Padeken J.
SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity.
Nat Struct Mol Biol 2022 29(2) 85-96 
[ PubMed ID = 35102319 ] [ RRC reference ]

Delaney CE, Methot SP, Guidi M, Katic I, Gasser SM, Padeken J.
Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65.
J Cell Biol 2019 218(3) 820-838 
[ PubMed ID = 30737265 ] [ RRC reference ]