分離済み変異体

tm6724

Allele Nametm6724
BalanceNot Required
OutCrossNot Accepted
Sequence NameH19N07.2
Gene Namemath-33
Worm BaseAllele Name tm6724
Gene Name math-33
Sequence H19N07.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 6706/6707-7352/7353 (646 bp deletion)
ChromosomeV
Putative gene structurejoin(4390..4601, 4656..4991, 5134..5600, 5767..6728, 6773..6890, 6935..7727, 7777..7891, 7945..8190, 8238..8310, 8420..8499)
Map position2.95
Balancer
Map position of balancer
Sequence of primersIntRev:TACCGGTCTTGTCATAAGTC,ExtFwd:GTACTTGGGATGGATAGCTG,ExtRev:CTTGTAGGCTCTGGGATCAT,IntFwd:AGGCATGTATTGACCATGCT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Campos JC, Wu Z, Rudich PD, Soo SK, Mistry M, Ferreira JC, Blackwell TK, Van Raamsdonk JM.
Mild mitochondrial impairment enhances innate immunity and longevity through ATFS-1 and p38 signaling.
EMBO Rep 2021 22(12) e52964 
[ PubMed ID = 34617666 ] [ RRC reference ]

Franz A, Valledor P, Ubieto-Capella P, Pilger D, Galarreta A, Lafarga V, Fernández-Llorente A, de la Vega-Barranco G, den Brave F, Hoppe T, Fernandez-Capetillo O, Lecona E.
USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork.
Cell Rep 2021 37(2) 109819 
[ PubMed ID = 34644576 ] [ RRC reference ]

McDiarmid TA, Belmadani M, Liang J, Meili F, Mathews EA, Mullen GP, Hendi A, Wong WR, Rand JB, Mizumoto K, Haas K, Pavlidis P, Rankin CH.
Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation.
Proc Natl Acad Sci U S A 2020 117(1) 656-667 
[ PubMed ID = 31754030 ] [ RRC reference ]

Senchuk MM, Dues DJ, Schaar CE, Johnson BK, Madaj ZB, Bowman MJ, Winn ME, Van Raamsdonk JM.
Activation of DAF-16/FOXO by reactive oxygen species contributes to longevity in long-lived mitochondrial mutants in Caenorhabditis elegans.
PLoS Genet 2018 14(3) e1007268 
[ PubMed ID = 29522556 ] [ RRC reference ]