分離済み変異体

tm6709

Allele Nametm6709
BalanceCompleted
OutCrossNot Accepted
Sequence NameB0348.6
Gene Nameife-3
Worm BaseAllele Name tm6709 (x1)
Gene Name ife-3
Sequence B0348.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 2325/2326-2747/2748 (422 bp deletion)
ChromosomeV
Putative gene structurecomplement(join(1907..2081, 2129..2355, 2404..2580, 2622..2789))
Map position-20.07
BalancernT1 [qIs51]
Map position of balancer
Sequence of primersExtFwd:GGAAGCTCATTTACGGTGAG,IntFwd:TATGCTTAAGGAGTTGGGGT,ExtRev:TTATTGTGCCCGATGTTACC,IntRev:GCCCGATGTTACCAATTACA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Thapa P, Chikale RV, Szulc NA, Pandrea MT, Sztyler A, Jaggi K, Niklewicz M, Serwa RA, Hoppe T, Pokrzywa W.
HSP70 inhibits CHIP E3 ligase activity to maintain germline function in Caenorhabditis elegans.
J Biol Chem 2024 300(11) 107864 
[ PubMed ID = 39384041 ] [ RRC reference ]

Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Zeng C, Weng C, Wang X, Yan YH, Li WJ, Xu D, Hong M, Liao S, Dong MQ, Feng X, Xu C, Guang S.
Functional Proteomics Identifies a PICS Complex Required for piRNA Maturation and Chromosome Segregation.
Cell Rep 2019 27(12) 3561-3572.e3 
[ PubMed ID = 31216475 ] [ RRC reference ]