Home > 分離済み変異体 > tm669

分離済み変異体

Allele Name		tm669
Balance		Not Required
OutCross		Not Accepted
Sequence Name		B0280.12
Gene Name		glr-2
Worm Base	Allele Name	tm669
	Gene Name	glr-2
	Sequence	B0280.12
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. G. Jansen: WT chemotaxix to NaCl. Dr. K. Ashrafi: normal Nile Red staining. Dr. I. Mori: normal thermotaxix at 20C.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		37534/37535-AT-38583/38584 (1049 bp deletion + 2 bp insertion)
Chromosome		III
Putative gene structure		complement(join(36648..37029, 37095..37322, 37717..37811, 37859..37959, 38004..38101, 38148..38308, 38776..38970, 39035..39185, 39538..39689, 39733..40000, 40568..40723, 40767..40858, 40903..41031))
Map position		-0.78
Balancer
Map position of balancer
Sequence of primers		ExtFwd:GCCTCTAGGCAGGTTATCAT,IntRev:CCGCAAAAAGTAACCTCTAC,IntFwd:CAGGCGTGGTGTTTCCTTTT,ExtRev:AAGCGCAATGAACCGCAAAA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Kramer TS, Wan FK, Pugliese SM, Atanas AA, Hiser AW, Luo J, Bueno E, Flavell SW. Neural Sequences Underlying Directed Turning in C. elegans. bioRxiv 2024    [ PubMed ID = 39149398 ] [ RRC reference ] Rawsthorne H, Calahorro F, Holden-Dye L, O' Connor V, Dillon J. Investigating autism associated genes in C. elegans reveals candidates with a role in social behaviour. PLoS One 2021 16(5) e0243121  [ PubMed ID = 34043629 ] [ RRC reference ] Hardaway JA, Sturgeon SM, Snarrenberg CL, Li Z, Xu XZ, Bermingham DP, Odiase P, Spencer WC, Miller DM 3rd, Carvelli L, Hardie SL, Blakely RD. Glial Expression of the Caenorhabditis elegans Gene swip-10 Supports Glutamate Dependent Control of Extrasynaptic Dopamine Signaling. J Neurosci 2015 35(25) 9409-23  [ PubMed ID = 26109664 ] [ RRC reference ] Hukema RK, Rademakers S, Jansen G. Gustatory plasticity in C. elegans involves integration of negative cues and NaCl taste mediated by serotonin, dopamine, and glutamate. Learn Mem 2008 15(11) 829-36  [ PubMed ID = 18984564 ] [ RRC reference ]