Home > 分離済み変異体 > tm666

分離済み変異体

Allele Name		tm666
Balance		Not Required
OutCross		Not Accepted
Sequence Name		Y39B6A.20
Gene Name		asp-1
Worm Base	Allele Name	tm666
	Gene Name	asp-1
	Sequence	Y39B6A.20
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. N. Tavernarakis: normal development, normal locomotion, slightly shorter, less progeny at 25C, starved appearance.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		92584/92585-TTTA-93065/93066 (481 bp deletion + 4 bp insertion)
Chromosome		V
Putative gene structure		complement(91506..92696)
Map position		18.5
Balancer
Map position of balancer
Sequence of primers		ExtRev:CGAATGACGTAAAAGGAGGA,IntRev:TAAAAGGAGGAGGGGGGTTG,ExtFwd:GTTTCCGATATCGTAGACGT,IntFwd:CAGTATTGACGGATGAAGGT
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Cheng W, Dai W, Chen W, Xue H, Zhao Z, Jiang Z, Li H, Liu J, Huang F, Cai M, Zheng L, Yu Z, Peng D, Zhang J. Nematodes exposed to furfural acetone exhibit a species-specific vacuolar H+-ATPase response. Ecotoxicol Environ Saf 2024 288 117407  [ PubMed ID = 39603226 ] [ RRC reference ] Zárate-Potes A, Yang W, Pees B, Schalkowski R, Segler P, Andresen B, Haase D, Nakad R, Rosenstiel P, Tetreau G, Colletier JP, Schulenburg H, Dierking K. The C. elegans GATA transcription factor elt-2 mediates distinct transcriptional responses and opposite infection outcomes towards different Bacillus thuringiensis strains. PLoS Pathog 2020 16(9) e1008826  [ PubMed ID = 32970778 ] [ RRC reference ] Lancaster BR, McGhee JD. How affinity of the ELT-2 GATA factor binding to cis-acting regulatory sites controls Caenorhabditis elegans intestinal gene transcription. Development 2020 147(14)   [ PubMed ID = 32586978 ] [ RRC reference ] Kim DK, Lim HS, Kawasaki I, Shim YH, Vaikath NN, El-Agnaf OM, Lee HJ, Lee SJ. Anti-aging treatments slow propagation of synucleinopathy by restoring lysosomal function. Autophagy. 2016 12(10) 1849-1863.  [ PubMed ID = -1 ] [ RRC reference ] Zhang F, Peng D, Cheng C, Zhou W, Ju S, Wan D, Yu Z, Shi J, Deng Y, Wang F, Ye X, Hu Z, Lin J, Ruan L, Sun M. Bacillus thuringiensis Crystal Protein Cry6Aa Triggers Caenorhabditis elegans Necrosis Pathway Mediated by Aspartic Protease (ASP-1). PLoS Pathog 2016 12(1) e1005389  [ PubMed ID = 26795495 ] [ RRC reference ]