分離済み変異体

tm6658

Allele Nametm6658
BalanceNot Required
OutCrossNot Accepted
Sequence NameF48A11.5
Gene Nameubxn-3
Worm BaseAllele Name tm6658
Gene Name ubxn-3
Sequence F48A11.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 25563/25564-26613/26614 (1050 bp deletion)
ChromosomeII
Putative gene structurecomplement(join(23366..23566, 23620..23829, 23879..24182, 24347..24564, 24616..24750, 25163..25551, 25911..25983, 26099..26195, 26352..26566, 26613..26669))
Map position-15.77
Balancer
Map position of balancer
Sequence of primersExtRev:CGCACGCCTCGTTTTCTCGT,IntFwd:AACGCTGAAATTGCACGGTC,ExtFwd:GACCTGACGCGCAACTTGAG,IntRev:GTCCGGGTCTCGACGAGAAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Franz A, Valledor P, Ubieto-Capella P, Pilger D, Galarreta A, Lafarga V, Fernández-Llorente A, de la Vega-Barranco G, den Brave F, Hoppe T, Fernandez-Capetillo O, Lecona E.
USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork.
Cell Rep 2021 37(2) 109819 
[ PubMed ID = 34644576 ] [ RRC reference ]

Franz A, Pirson PA, Pilger D, Halder S, Achuthankutty D, Kashkar H, Ramadan K, Hoppe T.
Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression.
Nat Commun 2016 7 10612 
[ PubMed ID = 26842564 ] [ RRC reference ]