分離済み変異体

tm6608

Allele Nametm6608
BalanceNot Required
OutCrossNot Accepted
Sequence NameT04C4.1
Gene NameT04C4.1
Worm BaseAllele Name tm6608
Gene Name T04C4.1
Sequence T04C4.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 13980/13981-TAAAGTTTTTGGGTCCCGCAGCGAGGGGTACTGTAGCTTTCTATTTTTCGCTGCGAGACCCAACTTTTTTTCAAATTTACCCGAACCTAGTCATGATTAT-14682/14683 (702 bp deletion + 100 bp insertion)
ChromosomeIV
Putative gene structurejoin(9776..9862, 10204..10279, 11091..11372, 11672..11816, 14454..14848, 15632..15789, 16397..16668, 17170..17480, 18068..18336, 18790..19040, 20938..21280, 22889..23023)
Map position-8.94
Balancer
Map position of balancer
Sequence of primersIntRev:GACCCTAAAGCTACAGTAAC,ExtRev:GTCGAGACCCTAAAGCTACA,IntFwd:CAATCTGCTGCTTTCTGCTA,ExtFwd:AGAGTGGGTCTCGCCATGAA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Zheng H, Peng K, Gou X, Ju C, Zhang H.
RNA recruitment switches the fate of protein condensates from autophagic degradation to accumulation.
J Cell Biol 2023 222(6)  
[ PubMed ID = 37014300 ] [ RRC reference ]

Zhang G, Wang Z, Du Z, Zhang H.
mTOR Regulates Phase Separation of PGL Granules to Modulate Their Autophagic Degradation.
Cell 2018 174(6) 1492-1506.e22 
[ PubMed ID = 30173914 ] [ RRC reference ]