分離済み変異体

tm658

Allele Nametm658
BalanceNot Required
OutCrossNot Accepted
Sequence NameF56A3.5
Gene Namebro-1
Worm BaseAllele Name tm658
Gene Name bro-1
Sequence F56A3.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. J. Lee: intron deletion. Dr. M. Herman: Dyf(+).
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 16853/16854-AGGAGAGAG-17313/17314 (460 bp deletion + 9 bp insertion)
ChromosomeI
Putative gene structurejoin(15956..16120, 16553..16618, 17360..17587)
Map position-0.3
Balancer
Map position of balancer
Sequence of primersExtRev:CCGTTCAATTCACGAAGCAT,IntRev:GGACCTGCGAGTTGTAACAA,IntFwd:CCGACAACATTTGTCGGTGA,ExtFwd:TTCTTGTGACTCCGCCTCCT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Kagoshima H, Nimmo R, Saad N, Tanaka J, Miwa Y, Mitani S, Kohara Y, Woollard A.
The C. elegans CBFbeta homologue BRO-1 interacts with the Runx factor, RNT-1, to promote stem cell proliferation and self-renewal.
Development 2007 134(21) 3905-15 
[ PubMed ID = 17933794 ] [ RRC reference ]

Ji YJ, Singaravelu G, Ahnn J.
RNT-1 regulation in C. elegans.
J Cell Biochem 2005 96(1) 8-15 
[ PubMed ID = 15988754 ] [ RRC reference ]