分離済み変異体

tm6556

Allele Nametm6556
BalanceNot Required
OutCrossNot Accepted
Sequence NameK10D6.1
Gene Namelgc-49
Worm BaseAllele Name tm6556
Gene Name lgc-49
Sequence K10D6.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 3425/3426-4150/4151 (725 bp deletion)
ChromosomeV
Putative gene structurejoin(1925..2071, 3486..3705, 3814..3893, 3953..4045, 4098..4174, 4480..4528, 4580..4905, 4954..5404, 5462..5539)
Map position2.97
Balancer
Map position of balancer
Sequence of primersIntRev:AGATCACCGGTCTAAATCAC,ExtRev:GGGACCTACATTCCTGTGAC,IntFwd:TAGTCTCGTGGTGCAAAGTC,ExtFwd:AGACTTTCCAGCTGCTTGCA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Zou W, Fan Y, Liu J, Cheng H, Hong H, Al-Sheikh U, Li S, Zhu L, Li R, He L, Tang YQ, Zhao G, Zhang Y, Wang F, Zhan R, Zheng X, Kang L.
Anoctamin-1 is a core component of a mechanosensory anion channel complex in C. elegans.
Nat Commun 2025 16(1) 1680 
[ PubMed ID = 39956854 ] [ RRC reference ]

Zhan X, Chen C, Niu L, Du X, Lei Y, Dan R, Wang ZW, Liu P.
Locomotion modulates olfactory learning through proprioception in C. elegans.
Nat Commun 2023 14(1) 4534 
[ PubMed ID = 37500635 ] [ RRC reference ]

Hori S, Mitani S.
The transcription factor unc-130/FOXD3/4 contributes to the biphasic calcium response required to optimize avoidance behavior.
Sci Rep 2022 12(1) 1907 
[ PubMed ID = 35115609 ] [ RRC reference ]

Takayanagi-Kiya S, Zhou K, Jin Y.
Release-dependent feedback inhibition by a presynaptically localized ligand-gated anion channel.
Elife 2016 5  
[ PubMed ID = 27782882 ] [ RRC reference ]