分離済み変異体

tm6523

Allele Nametm6523
Allele Type通常株
Sequence NameF01G12.2
Gene Namesur-7
Worm BaseAllele Name tm6523
Gene Name sur-7
Sequence F01G12.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 8402/8403-TTTT-8966/8967 (564 bp deletion + 4 bp insertion)
ChromosomeX
Putative gene structurejoin(7734..7770, 7904..8152, 8453..8748, 8942..9043, 9256..9390)
Map position23.91
Balancer
Map position of balancer
Sequence of primersExtFwd:CCACTCTGTAGGTTCTAGTA,IntFwd:AGTTCAAAGGTACTCTGCAC,ExtRev:TCGCGGGCTCAATACCTGTG,IntRev:GGTCTGGGGACCACTTGTTC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Hu Y, Wang Y, Wang X, Wu X, Fu L, Liu X, Wen Y, Sheng J, Zhang J.
The role of cation diffusion facilitator CDF-1 in lipid metabolism in Caenorhabditis elegans.
G3 (Bethesda) 2021 11(7)  
[ PubMed ID = 33871589 ] [ RRC reference ]

Zhang JJ, Hao JJ, Zhang YR, Wang YL, Li MY, Miao HL, Zou XJ, Liang B.
Zinc mediates the SREBP-SCD axis to regulate lipid metabolism in Caenorhabditis elegans.
J Lipid Res 2017 58(9) 1845-1854 
[ PubMed ID = 28710073 ] [ RRC reference ]