分離済み変異体

tm651

Allele Name

tm651

Balance

Request Available

OutCross

Not Accepted

Sequence Name

R13F6.4

Gene Name

ten-1

Worm Base

Allele Name

tm651

Gene Name

ten-1

Sequence

R13F6.4

Phenotype

lethal or sterile. Dr. J. Kaplan: wild type movement, nonEgl, nonRic.

Mutation site

3657/3658-4550/4551(890 bp deletion)

Chromosome

III

Putative gene structure

join(31521..31880, 32025..32079, 3443..3541, 3605..3786, 3878..4049, 4101..5371, 5424..6668, 6716..7231, 7284..8383, 8447..8803, 9050..10970, 11019..11670, 11752..12363)

Map position

-0.94

Balancer

Map position of balancer

Sequence of primers

ExtFwd:ACGTCTGGAGGAGCACCGAA,ExtRev:CACATTCGCCTTTTCCGGAA,IntFwd:CCCAACGTATTCGGATGCAT,IntRev:CACTGATTTGGACATCCATC

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Topf U, Drabikowski K.
Ancient Function of Teneurins in Tissue Organization and Neuronal Guidance in the Nematode Caenorhabditis elegans.
Front Neurosci 2019 13 205
[ PubMed ID = 30906249 ] [ RRC reference ]

Topf U, Chiquet-Ehrismann R.
Genetic interaction between Caenorhabditis elegans teneurin ten-1 and prolyl 4-hydroxylase phy-1 and their function in collagen IV-mediated basement membrane integrity during late elongation of the embryo.
Mol Biol Cell 2011 22(18) 3331-43
[ PubMed ID = 21795395 ] [ RRC reference ]

Mörck C, Vivekanand V, Jafari G, Pilon M.
C. elegans ten-1 is synthetic lethal with mutations in cytoskeleton regulators, and enhances many axon guidance defective mutants.
BMC Dev Biol 2010 10 55
[ PubMed ID = 20497576 ] [ RRC reference ]

Trzebiatowska A, Topf U, Sauder U, Drabikowski K, Chiquet-Ehrismann R.
Caenorhabditis elegans teneurin, ten-1, is required for gonadal and pharyngeal basement membrane integrity and acts redundantly with integrin ina-1 and dystroglycan dgn-1.
Mol Biol Cell 2008 19(9) 3898-908
[ PubMed ID = 18632986 ] [ RRC reference ]