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分離済み変異体

Allele Name		tm6471
Balance		Completed
OutCross		Not Accepted
Sequence Name		ZC434.6
Gene Name		aph-2
Worm Base	Allele Name	tm6471 (x1)
	Gene Name	aph-2
	Sequence	ZC434.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		12257/12258-13496/13497 (1239 bp deletion)
Chromosome		I
Putative gene structure		join(11856..12000, 12455..13040, 13389..13727, 14095..14343, 14615..14867, 15078..15338, 15391..15658, 16231..16301)
Map position		4.93
Balancer		hT2
Map position of balancer
Sequence of primers		IntRev:GATGCACCCACCTATCTCCA,ExtRev:TCACCTATCCATGGCTGAAG,IntFwd:TGCCGAAGACGATACTCTAT,ExtFwd:AACGCACGAATTCGGTTGTC
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Brinkley DM, Smith KC, Fink EC, Kwen W, Yoo NH, West Z, Sullivan NL, Farthing AS, Hale VA, Goutte C. Notch signaling without the APH-2/nicastrin subunit of gamma secretase in Caenorhabditis elegans germline stem cells. Genetics 2024 227(3)   [ PubMed ID = 38717968 ] [ RRC reference ]