分離済み変異体

tm6452

Allele Nametm6452
BalanceNot Required
OutCrossNot Accepted
Sequence NameK08H10.1
Gene Namelea-1
Worm BaseAllele Name tm6452
Gene Name lea-1
Sequence K08H10.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 37243/37244-AAAAAAAAAAAAAAAAAAAA-37699/37700 (456 bp deletion + 20 bp insertion)
ChromosomeV
Putative gene structurejoin(24915..24953, 26257..26463, 33537..33650, 33695..34477, 34526..35092, 35188..35526, 35669..36040, 36551..37891, 37946..38011, 38527..38703, Z73975.1:221..301, Z73975.1:1373..1480)
Map position2.23
Balancer
Map position of balancer
Sequence of primersIntFwd:GCATGTATCTTCAGTGTCCT,ExtRev:GTATCATGGGCAGCTTCCGA,IntRev:ACATGTGCTCCGTGCATATA,ExtFwd:GTCCTCGATTCCCATTGATC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Dejima K, Imae R, Suehiro Y, Yoshida K, Mitani S.
An endomembrane zinc transporter negatively regulates systemic RNAi in Caenorhabditis elegans.
iScience 2023 26(6) 106930 
[ PubMed ID = 37305693 ] [ RRC reference ]

Hibshman JD, Goldstein B.
LEA motifs promote desiccation tolerance in vivo.
BMC Biol 2021 19(1) 263 
[ PubMed ID = 34903234 ] [ RRC reference ]