分離済み変異体

tm6360

Allele Nametm6360
BalanceNot Required
OutCrossNot Accepted
Sequence NameY55B1AL.2
Gene NameY55B1AL.2
Worm BaseAllele Name tm6360
Gene Name Y55B1AL.2
Sequence Y55B1AL.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 2950/2951-3297/3298 (347 bp deletion)
ChromosomeIII
Putative gene structurecomplement(join(3146..3253, 3556..3663))
Map position-26.71
Balancer
Map position of balancer
Sequence of primersExtFwd:CCCTCCACACATTCTCAGAC,IntRev:AGCGAATTCAATCATCGCCA,ExtRev:ACTAGTTCAAGAGCTCGGCA,IntFwd:AAGGACGGATTAGATGGCTG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Muniesa-Vargas A, Davó-Martínez C, Ribeiro-Silva C, van der Woude M, Thijssen KL, Haspels B, Häckes D, Kaynak ÜU, Kanaar R, Marteijn JA, Theil AF, Kuijten MMP, Vermeulen W, Lans H.
Persistent TFIIH binding to non-excised DNA damage causes cell and developmental failure.
Nat Commun 2024 15(1) 3490 
[ PubMed ID = 38664429 ] [ RRC reference ]

Thijssen KL, van der Woude M, Davó-Martínez C, Dekkers DHW, Sabatella M, Demmers JAA, Vermeulen W, Lans H.
C. elegans TFIIH subunit GTF-2H5/TTDA is a non-essential transcription factor indispensable for DNA repair.
Commun Biol 2021 4(1) 1336 
[ PubMed ID = 34824371 ] [ RRC reference ]