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分離済み変異体

Allele Name		tm6321
Balance		Completed
OutCross		Not Accepted
Sequence Name		W02B12.9
Gene Name		mfn-1
Worm Base	Allele Name	tm6321 (x1)
	Gene Name	mfn-1
	Sequence	W02B12.9
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		Let or Ste.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		26669/26670-27063/27064 (394 bp deletion)
Chromosome		II
Putative gene structure		complement(join(25449..25529, 25991..26095, 26154..26852, 27047..27100))
Map position		3.49
Balancer		mnC1 [dpy-10(e128) unc52(e444) nIs190 let-?]
Map position of balancer
Sequence of primers		IntRev:ACGAGACTCTCCCTCCTCCT,ExtFwd:TACCTGGAATATGACCCTAG,ExtRev:ATCCCCTCTGCCTACTTCCA,IntFwd:TGACCCTAGCTTGTAATCCA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Zeidan RS, Ebea-Ugwuanyi P, Sykes S, Evripidou N, Pan E, Markovich Z, Sheng Y, Han SM, Leeuwenburgh C, Xiao R. Exploring age-related iron dysregulation: effects on longevity, body size, and behavior in C. elegans. Exp Gerontol 2025 208 112826  [ PubMed ID = 40617521 ] [ RRC reference ] Thapa P, Chikale RV, Szulc NA, Pandrea MT, Sztyler A, Jaggi K, Niklewicz M, Serwa RA, Hoppe T, Pokrzywa W. HSP70 inhibits CHIP E3 ligase activity to maintain germline function in Caenorhabditis elegans. J Biol Chem 2024 300(11) 107864  [ PubMed ID = 39384041 ] [ RRC reference ]