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分離済み変異体

Allele Name		tm6235
Balance		Not Required
OutCross		Not Accepted
Sequence Name		Y49A10A.1
Gene Name		efhc-1
Worm Base	Allele Name	tm6235
	Gene Name	efhc-1
	Sequence	Y49A10A.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		6709/6710-7492/7493 (783 bp deletion)
Chromosome		X
Putative gene structure		join(6061..6251, 6482..7019, 7063..7160, 7204..7313, 7360..7520, 7611..7682, 7732..7877, 7922..8042)
Map position		1.98
Balancer
Map position of balancer
Sequence of primers		ExtFwd:TACCTTTCCATGTAACCCAC,IntFwd:TACCGCGTCGTTTCCGACGT,ExtRev:GACCGTACAATACAGAAGGA,IntRev:ACAGAAGGAGCATCAACCTA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Loucks CM, Park K, Walker DS, McEwan AH, Timbers TA, Ardiel EL, Grundy LJ, Li C, Johnson JL, Kennedy J, Blacque OE, Schafer W, Rankin CH, Leroux MR. EFHC1, implicated in juvenile myoclonic epilepsy, functions at the cilium and synapse to modulate dopamine signaling. Elife 2019 8   [ PubMed ID = 30810526 ] [ RRC reference ] Loucks CM, Bialas NJ, Dekkers MP, Walker DS, Grundy LJ, Li C, Inglis PN, Kida K, Schafer WR, Blacque OE, Jansen G, Leroux MR. PACRG, a protein linked to ciliary motility, mediates cellular signaling. Mol Biol Cell 2016 27(13) 2133-44  [ PubMed ID = 27193298 ] [ RRC reference ]