分離済み変異体

tm6232

Allele Nametm6232
BalanceNot Required
OutCrossNot Accepted
Sequence NameF37A8.4
Gene Namenlp-10
Worm BaseAllele Name tm6232
Gene Name nlp-10
Sequence F37A8.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 8020/8021-8856/8857 (836 bp deletion)
ChromosomeIII
Putative gene structurecomplement(join(7470..7573, 7863..8003, 8398..8490, 9498..9555))
Map position-4.1
Balancer
Map position of balancer
Sequence of primersExtFwd:AAACATCGATCCTAACGCAC,IntFwd:CCCCCAATTGGAATGAGATC,ExtRev:GCCCCCGTTCTCTTCTGTTC,IntRev:TCCCCTCCGCATTCTTTGTA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Aoki I, Golinelli L, Dunkel E, Bhat S, Bassam E, Beets I, Gottschalk A.
Hierarchical regulation of functionally antagonistic neuropeptides expressed in a single neuron pair.
Nat Commun 2024 15(1) 9504 
[ PubMed ID = 39489735 ] [ RRC reference ]

Liu H, Wu JJ, Li R, Wang PZ, Huang JH, Xu Y, Zhao JL, Wu PP, Li SJ, Wu ZX.
Disexcitation in the ASH/RIM/ADL negative feedback circuit fine-tunes hyperosmotic sensation and avoidance in Caenorhabditis elegans.
Front Mol Neurosci 2023 16 1101628 
[ PubMed ID = 37008778 ] [ RRC reference ]

Levi-Ferber M, Shalash R, Le-Thomas A, Salzberg Y, Shurgi M, Benichou JI, Ashkenazi A, Henis-Korenblit S.
Neuronal regulated ire-1-dependent mRNA decay controls germline differentiation in Caenorhabditis elegans.
Elife 2021 10  
[ PubMed ID = 34477553 ] [ RRC reference ]

Yu Y, Zhi L, Guan X, Wang D, Wang D.
FLP-4 neuropeptide and its receptor in a neuronal circuit regulate preference choice through functions of ASH-2 trithorax complex in Caenorhabditis elegans.
Sci Rep 2016 6 21485 
[ PubMed ID = 26887501 ] [ RRC reference ]