分離済み変異体

tm6232

Allele Nametm6232
BalanceNot Required
OutCrossNot Accepted
Sequence NameF37A8.4
Gene Namenlp-10
Worm BaseAllele Name tm6232
Gene Name nlp-10
Sequence F37A8.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 8020/8021-8856/8857 (836 bp deletion)
ChromosomeIII
Putative gene structurecomplement(join(7470..7573, 7863..8003, 8398..8490, 9498..9555))
Map position-4.1
Balancer
Map position of balancer
Sequence of primersExtFwd:AAACATCGATCCTAACGCAC,IntFwd:CCCCCAATTGGAATGAGATC,ExtRev:GCCCCCGTTCTCTTCTGTTC,IntRev:TCCCCTCCGCATTCTTTGTA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Wang PZ, Ge MH, Su P, Wu PP, Wang L, Zhu W, Li R, Liu H, Wu JJ, Xu Y, Zhao JL, Li SJ, Wang Y, Chen LM, Wu TH, Wu ZX.
Sensory plasticity caused by up-down regulation encodes the information of short-term learning and memory.
iScience 2025 28(4) 112215 
[ PubMed ID = 40224011 ] [ RRC reference ]

Chen YC, Zang KE, Ahamed H, Ringstad N.
Food sensing controls C. elegans reproductive behavior by neuromodulatory disinhibition.
Sci Adv 2025 11(16) eadu5829 
[ PubMed ID = 40238881 ] [ RRC reference ]

Aoki I, Golinelli L, Dunkel E, Bhat S, Bassam E, Beets I, Gottschalk A.
Hierarchical regulation of functionally antagonistic neuropeptides expressed in a single neuron pair.
Nat Commun 2024 15(1) 9504 
[ PubMed ID = 39489735 ] [ RRC reference ]

Liu H, Wu JJ, Li R, Wang PZ, Huang JH, Xu Y, Zhao JL, Wu PP, Li SJ, Wu ZX.
Disexcitation in the ASH/RIM/ADL negative feedback circuit fine-tunes hyperosmotic sensation and avoidance in Caenorhabditis elegans.
Front Mol Neurosci 2023 16 1101628 
[ PubMed ID = 37008778 ] [ RRC reference ]

Levi-Ferber M, Shalash R, Le-Thomas A, Salzberg Y, Shurgi M, Benichou JI, Ashkenazi A, Henis-Korenblit S.
Neuronal regulated ire-1-dependent mRNA decay controls germline differentiation in Caenorhabditis elegans.
Elife 2021 10  
[ PubMed ID = 34477553 ] [ RRC reference ]

Yu Y, Zhi L, Guan X, Wang D, Wang D.
FLP-4 neuropeptide and its receptor in a neuronal circuit regulate preference choice through functions of ASH-2 trithorax complex in Caenorhabditis elegans.
Sci Rep 2016 6 21485 
[ PubMed ID = 26887501 ] [ RRC reference ]