分離済み変異体

tm6082

Allele Nametm6082
BalanceNot Required
OutCrossNot Accepted
Sequence NameC43H8.2
Gene Namemafr-1
Worm BaseAllele Name tm6082
Gene Name mafr-1
Sequence C43H8.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 4494/4495-4708/4709 (214 bp deletion)
ChromosomeI
Putative gene structurejoin(3902..3984, 4035..4374, 4424..4545, 4597..4789)
Map position5.06
Balancer
Map position of balancer
Sequence of primersExtFwd:TACACAGAAGTTGCCGACAG,IntFwd:TACGTAGGATTTTTCCGCAC,ExtRev:GCCGGCAAGACTAATACTAT,IntRev:ATGGACGTGTCGGCTTGTTT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Pradhan A, Hammerquist AM, Khanna A, Curran SP.
The C-Box Region of MAF1 Regulates Transcriptional Activity and Protein Stability.
J Mol Biol 2017 429(2) 192-207 
[ PubMed ID = 27986570 ] [ RRC reference ]

Cai Y, Wei YH.
Stress resistance and lifespan are increased in C. elegans but decreased in S. cerevisiae by mafr-1/maf1 deletion.
Oncotarget 2016 7(10) 10812-26 
[ PubMed ID = 26934328 ] [ RRC reference ]